Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Mouse IDO1 Protein (1-407 aa), His-tagged

Cat.No. : IDO1-2077M
Product Overview : Recombinant Mouse IDO1 Protein (1-407 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Signal Transduction. Protein Description: Full Length.
  • Specification
  • Gene Information
  • Related Products
Description : Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway. Involved in the peripheral immune tolerance, contributing to maintain homeostasis by preventing autoimmunity or immunopathology that would result from uncontrolled and overreacting immune responses. Tryptophan shortage inhibits T lymphocytes division and accumulation of tryptophan catabolites induces T-cell apoptosis and differentiation of regulatory T-cells. Acts as a suppressor of anti-tumor immunity (PubMed:25691885). Limits the growth of intracellular pathogens by depriving tryptophan. Protects the fetus from maternal immune rejection.
Source : Yeast
Species : Mouse
Tag : His
Form : Tris-based buffer,50% glycerol
Molecular Mass : 47.6 kDa
Protein length : 1-407 aa
AA Sequence : MALSKISPTEGSRRILEDHHIDEDV GFALPHPLVELPDAYSPWVLVARNL PVLIENGQLREEVEKLPTLSTDGLR GHRLQRLAHLALGYITMAYVWNRGD DDVRKVLPRNIAVPYCELSEKLGLP PILSYADCVLANWKKKDPNGPMTYE NMDILFSFPGGDCDKGFFLVSLLVE IAASPAIKAIPTVSSAVERQDLKAL EKALHDIATSLEKAKEIFKRMRDFV DPDTFFHVLRIYLSGWKCSSKLPEG LLYEGVWDTPKMFSGGSAGQSSIFQ SLDVLLGIKHEAGKESPAEFLQEMR EYMPPAHRNFLFFLESAPPVREFVI SRHNEDLTKAYNECVNGLVSVRKFH LAIVDTYIMKPSKKKPTDGDKSEEP SNVESRGTGGTNPMTFLRSVKDTTE KALLSWP
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with reconstitution instruction is sent along with the products.
Gene Name : Ido1 indoleamine 2,3-dioxygenase 1 [ Mus musculus ]
Official Symbol : IDO1
Synonyms : IDO1; indoleamine 2,3-dioxygenase 1; IDO-1; indole 2,3-dioxygenase; Ido; Indo;
Gene ID : 15930
mRNA Refseq : NM_008324
Protein Refseq : NP_032350
UniProt ID : P28776

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (3)

Write a review
Reviews
08/12/2022

    The product was kept in perfect condition and delivered on time so that I got the perfect product in the shortest time possible.

    05/14/2022

      Customer service contacted me in a timely manner and helped me solve a lot of problems that arose in my experiments.

      03/12/2022

        The purchased proteins helped me to get satisfactory experimental results.

        Ask a Question for All IDO1 Products

        Required fields are marked with *

        My Review for All IDO1 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends