Recombinant Active Human IGF1 Protein, Fc-His-tagged(C-ter)
Cat.No. : | IGF1-126H |
Product Overview : | Recombinant Active Human IGF1 Protein with Fc-His tag (C-ter) was expressed in HEK293. |
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Description : | The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015] |
Source : | HEK293 |
Species : | Human |
Tag : | His&Fc |
Form : | Powder |
Bio-activity : | Measured by its ability to stimulate p70 S6 Kinase (Thr389) and p85 S6 Kinase (Thr412) autophosphorylation in 293T human embryonic kidney cells. 0.01-1 ng/mL of Recombinant Human IGF1 can effectively enhance p70 S6 Kinase (Thr389) and p85 S6 Kinase (Thr412) autophosphorylation. Measured in a cell proliferation assay using MCF-7 cells. The ED50 for this effect is typically 7.5-30 ng/mL. |
Protein length : | Gly49-Ala118 |
Endotoxin : | Endotoxin level is less than 0.1 EU/μg of the protein, as determined by the LAL test. |
Purity : | > 87% (by SDS-PAGE) |
Applications : | Binding, FuncSt, SDS-PAGE |
Notes : | For laboratory research only, not for drug, diagnostic or other use. |
Storage : | Lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C for up to one month, at 2-8°C for up to one week. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
Storage Buffer : | PBS (pH 7.4) |
Reconstitution : | Reconstitute to a concentration of 0.1-0.5 mg/ml in sterile distilled water. |
Gene Name : | IGF1 insulin-like growth factor 1 (somatomedin C) [ Homo sapiens ] |
Official Symbol : | IGF1 |
Synonyms : | IGF1; insulin-like growth factor 1 (somatomedin C); insulin-like growth factor 1; IGF1A; MGF; IGF-IA; IGF-IB; somatomedin-C; mechano growth factor; insulin-like growth factor I; insulin-like growth factor IA; insulin-like growth factor IB; IGFI; IGF-I; |
Gene ID : | 3479 |
mRNA Refseq : | NM_000618 |
Protein Refseq : | NP_000609 |
MIM : | 147440 |
UniProt ID : | P05019 |
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Not For Human Consumption!
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Customer Reviews (3)
Write a reviewRange of applications of IGF1 is breathtaking, and it can play its unique advantage in any field.
The biological activity and high purity of the protein are impressive, which is why it is a trusted partner in the field of scientific research.
IGF1 can preserve its stability under extreme conditions, such as at high or low temperatures, which is very beneficial for our experiments.
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