Recombinant Active Human IL17RA Protein (ECD), His-tagged(C-ter)
Cat.No. : | IL17RA-153H |
Product Overview : | Recombinant Active Human IL17RA Protein (ECD) with His tag (C-ter) was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014] |
Source : | HEK293 |
Species : | Human |
Tag : | His(C-ter) |
Form : | Powder |
Bio-activity : | Measured by its ability to inhibit IL-17A induced IL-6 secretion by HeLa cells. The ED50 for this effect is 0.02-0.1 μg/mL in the presence of 10 ng/mL recombinant human IL-17A. |
Protein Length : | Leu33-Trp320 |
Endotoxin : | Endotoxin level is less than 0.1 EU/μg of the protein, as determined by the LAL test. |
Purity : | > 95% (by SDS-PAGE) |
Applications : | Binding, FuncSt, SDS-PAGE |
Notes : | For laboratory research only, not for drug, diagnostic or other use. |
Storage : | Lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C for up to one month, at 2-8°C for up to one week. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
Storage Buffer : | PBS (pH 7.4) |
Reconstitution : | Reconstitute to a concentration of 0.1-0.5 mg/ml in sterile distilled water. |
Gene Name : | IL17RA interleukin 17 receptor A [ Homo sapiens ] |
Official Symbol : | IL17RA |
Synonyms : | IL17RA; interleukin 17 receptor A; IL17R, interleukin 17 receptor; interleukin-17 receptor A; CD217; CDw217; hIL 17R; IL 17RA; IL-17 receptor A; IL17R; CANDF5; IL-17RA; hIL-17R; FLJ32274; FLJ36453; MGC10262; |
Gene ID : | 23765 |
mRNA Refseq : | NM_014339 |
Protein Refseq : | NP_055154 |
MIM : | 605461 |
UniProt ID : | Q96F46 |
Products Types
◆ Recombinant Protein | ||
IL17RA-313H | Recombinant Human IL17RA Protein, Fc-tagged | +Inquiry |
IL17RA-1167H | Recombinant Human IL17RA Protein, His (Fc)-Avi-tagged | +Inquiry |
IL17RA-2197H | Active Recombinant Human IL17RA protein(Met1-Trp320), His-tagged | +Inquiry |
IL17RA-449H | Recombinant Human IL17RA Protein (Met1-Trp320), His-Fc-tagged, Biotinylated | +Inquiry |
Il17ra-1240M | Recombinant Mouse Il17ra Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
IL17RA-1441RCL | Recombinant Rat IL17RA cell lysate | +Inquiry |
IL17RA-1070MCL | Recombinant Mouse IL17RA cell lysate | +Inquiry |
IL17RA-1252CCL | Recombinant Cynomolgus IL17RA cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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