• Official Full Name

    interleukin 17 receptor A

  • Background

    Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the;maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin;17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A.;Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as;rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure.
  • Synonyms

    CD217; IL17R; CANDF5; CDw217; IL-17RA; hIL-17R; interleukin-17 receptor A; IL-17 receptor A; Brodalumab; 1174395-19-7; Ixekizumab; 1143503-69-8;
    • Type:
    • Cell & Tissue Lysates
    • Recombinant Proteins
    • Protein Pre-coupled Magnetic Beads
    • Antibody
    • Species :
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human Cell
    • Insect cells
    • Mammalian Cell
    • Rabbit
    • Tag :
    • Avi|Fc
    • Fc
    • Fc|His
    • Avi
    • His
    • His (Fc)
    • His(C
    • ter)
    • His|Avi
    • His|Fc
    • His|T7
    • MYC
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Cynomolgus Monkey IL17RA-1252CCL Recombinant Cynomolgus IL17RA cell lysate Human Cell N/A
    Cynomolgus Monkey IL17RA-8838C Recombinant Cynomolgus IL17RA, Fc tagged Human Cell Fc
    Human IL17RA-220H Active Recombinant Human IL17RA Protein, Fc & Avi-tagged, Biotinylated HEK293 Avi/Fc
    Human IL17RA-373H Active Recombinant Human IL17RA protein, Fc-tagged HEK293 Fc
    Human IL17RA-2197H Recombinant Human IL17RA, His tagged Human Cell His
    Human IL17RA-2199H Recombinant Human IL17RA, Fc-His tagged Human Cell Fc/His
    Human IL17RA-2198H Active Recombinant Human IL17RA Protein, His & Avi-tagged, Biotinylated HEK293 His/Avi
    Human IL17RA-4873H Recombinant Human IL17RA Protein, Fc/His-tagged Insect cells Fc/His
    Human IL17RA-1740H Recombinant Human IL17RA protein, His-tagged E.coli His
    Human IL17RA-1741H Recombinant Human IL17RA protein, His-tagged E.coli His
    Human IL17RA-153H Recombinant Active Human IL17RA Protein (ECD), His-tagged(C-ter) HEK293 His(C-ter)
    Human IL17RA-208H Recombinant Human IL17RA protein, His-Avi-tagged HEK293 His-Avi
    Human IL17RA-449H Recombinant Human IL17RA Protein (Met1-Trp320), His-Fc-tagged, Biotinylated HEK293 His/Fc
    Human IL17RA-450H Recombinant Human IL17RA Protein (Met1-Trp320), His-tagged, Biotinylated HEK293 His
    Human IL17RA-1167H-B Recombinant Human IL17RA Protein Pre-coupled Magnetic Beads HEK293
    Human IL17RA-299H Recombinant Human IL17RA protein, Fc-Avi-tagged HEK293 Fc-Avi
    Human IL17RA-041H Recombinant Human IL17RA Protein, His-tagged E.coli His
    Human IL17RA-313H Recombinant Human IL17RA Protein, Fc-tagged HEK293 Fc
    Human IL17RA-0261H Recombinant Human IL17RA protein, His-tagged HEK293 His
    Human IL17RA-1167H Recombinant Human IL17RA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Human IL17RA-312H Recombinant Human IL17RA Protein, His-tagged HEK293 His
    Human IL17RA-2640HCL Recombinant Human IL17RA cell lysate Human Cell N/A
    Human CAB11561RH Rabbit Anti-Human Interleukin 17 Receptor A Monoclonal Antibody Rabbit N/A
    Mouse Il17ra-1742M Recombinant Mouse Il17ra protein, His-tagged E.coli His
    Mouse Il17ra-4026M Active Recombinant Mouse Il17ra, His tagged HEK293 His
    Mouse IL17RA-1070MCL Recombinant Mouse IL17RA cell lysate Human Cell N/A
    Mouse Il17ra-1240M Recombinant Mouse Il17ra Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Mouse IL17RA-404M Recombinant Mouse Il17ra, Fc tagged Human Cell His
    Rat Il17ra-1743R Recombinant Rat Il17ra protein, His & T7-tagged E.coli His/T7
    Rat IL17RA-1441RCL Recombinant Rat IL17RA cell lysate Human Cell N/A
    Rat IL17RA-164R Recombinant Rat Il17ra, Fc tagged Human Cell His
    Rat Il17ra-7453R Active Recombinant Rat Il17ra, His-tagged Human Cell His
    Rhesus IL17RA-442R Recombinant Rhesus IL17RA Protein, His-tagged HEK293 His
    Zebrafish IL17RA-5810Z Recombinant Zebrafish IL17RA Mammalian Cell His
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • IL17RA Related Gene Family
    • IL17RA Related Research Area

    IL17RA involved in several pathways and played different roles in them. We selected most pathways IL17RA participated on our site, such as Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL17RA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interactionFLT4;TNFRSF11B;TNFSF4;CCL27;CD40LG;CCL8;IFNA2;BMPR2A;PDGFAB

    IL17RA has several biochemical functions, for example, interleukin-17 receptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL17RA itself. We selected most functions IL17RA had, and list some proteins which have the same functions with IL17RA. You can find most of the proteins on our site.

    Function Related Protein
    interleukin-17 receptor activityIL17RE;IL17RD;IL17RB;IL17RC;IL17RA
    protein bindingBMP4;SPPL3;SOX9;KIAA1217;SNX20;CCDC110;PNMA5;NDFIP2;RAB2B

    IL17RA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL17RA here. Most of them are supplied by our site. Hope this information will be useful for your research of IL17RA.


    • Q&As
    • Reviews

    Q&As (10)

    Ask a question
    What experimental techniques are employed to investigate the interaction between IL17RA and various IL17 family members, and how is their binding specificity determined? 12/02/2022

    Surface plasmon resonance, co-immunoprecipitation, and mutagenesis studies reveal IL17RA's binding partners and affinity.

    Can you discuss the experimental designs used to examine the crosstalk between IL17RA signaling and other immune pathways, such as TNF-α or IFN-纬 pathways? 11/16/2020

    Cross-pathway signaling assays, gene expression profiling, and functional rescue experiments unveil IL17RA's interaction networks.

    What strategies are utilized to explore the contribution of IL17RA to tissue remodeling processes, such as angiogenesis and fibrosis? 11/08/2020

    Angiogenesis assays, fibroblast activation assays, and tissue remodeling models illuminate IL17RA's role in tissue repair.

    How is the potential of IL17RA as a therapeutic target evaluated in experimental settings, and what challenges exist in translating these findings to clinical applications? 03/15/2020

    Animal models, pharmacological interventions, and toxicity assessments evaluate IL17RA-targeted therapies and translational challenges.

    How do researchers study the involvement of IL17RA in autoimmune disorders through patient samples, and what insights have been gained? 12/26/2019

    Patient cohorts, clinical data analysis, and immune profiling provide insights into IL17RA's relevance in autoimmune diseases.

    How do researchers study the role of IL17RA in the regulation of immune cell recruitment and infiltration in inflammatory tissues? 12/13/2018

    Flow cytometry, in vivo imaging, and chemotaxis assays characterize immune cell responses guided by IL17RA activation.

    Can you elaborate on the methods used to dissect the intracellular signaling pathways triggered by IL17RA activation, especially in the context of autoimmune diseases? 04/28/2018

    Phosphorylation assays, gene expression analysis, and knockout models dissect IL17RA-mediated signaling cascades.

    Could you explain the experimental approaches employed to assess the impact of IL17RA inhibition on chronic inflammatory diseases in preclinical models? 01/10/2018

    Disease models, antibody-based treatments, and inflammatory biomarker assessments elucidate IL17RA's therapeutic potential.

    What molecular methods are employed to understand the genetic and epigenetic regulation of IL17RA expression in immune cells? 07/22/2017

    ChIP-sequencing, promoter analysis, and epigenetic modification studies uncover IL17RA gene regulation mechanisms.

    What techniques are used to investigate the role of IL17RA in maintaining epithelial barrier integrity and preventing microbial invasion? 03/06/2017

    Epithelial barrier assays, microbiome analysis, and infection models decipher IL17RA's role in mucosal defense.

    Customer Reviews (3)

    Write a review

      Effective in T-cell activation. -


        Suitable for co-immunoprecipitation. -


          High solubility. -

          Ask a Question for All IL17RA Products

          Required fields are marked with *

          My Review for All IL17RA Products

          Required fields are marked with *


          Stay Updated on the
          Latest Bioscience Trends

          Copyright © 2023 Creative BioMart. All Rights Reserved.

          Terms and Conditions        Privacy Policy