• Official Full Name

    interleukin 17 receptor A

  • Overview

    Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the;maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin;17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A.;Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as;rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure.
  • Synonyms

    CD217; IL17R; CANDF5; CDw217; IL-17RA; hIL-17R; interleukin-17 receptor A; IL-17 receptor A; Brodalumab; 1174395-19-7; Ixekizumab; 1143503-69-8;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Antibody
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Rhesus
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • Insect cells
  • Mammalian Cell
  • Mammalian cells
  • Rabbit
  • C
  • 6×His
  • Fc
  • hFc
  • His
  • Fc|His
  • Avi
  • Flag
  • His (Fc)
  • His(C
  • ter)
  • His|Fc
  • His|T7
  • MYC
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IL17RA-220H Active Recombinant Human IL17RA protein, hFc&Avi-tagged, Biotinylated HEK293 hFc&Avi Met1-Trp320
Human IL17RA-373H Active Recombinant Human IL17RA protein, Fc-tagged HEK293 Fc Leu 33 - Trp 320
Human IL17RA-2198H Active Recombinant Human IL17RA protein, His&Avi-tagged, Biotinylated HEK293 His&Avi Met1-Trp320
Human IL17RA-2199H BiotinylatedRecombinant Human IL17RA protein(Met1-Trp320), His&hFc-tagged HEK293 C-His&hFc Met1-Trp320
Human IL17RA-2197H Active Recombinant Human IL17RA protein(Met1-Trp320), His-tagged HEK293 C-His Met1-Trp320
Human IL17RA-1741H Recombinant Human IL17RA protein, His-tagged E.coli His Pro377~Phe534 (Accession # Q96F46)
Human IL17RA-1740H Recombinant Human IL17RA protein, His-tagged E.coli His Leu33~Asp172 (Accession # Q96F46)
Human IL17RA-2640HCL Recombinant Human IL17RA cell lysate Human Cell N/A
Human IL17RA-153H Recombinant Active Human IL17RA Protein (ECD), His-tagged(C-ter) HEK293 His(C-ter) Leu33-Trp320
Human IL17RA-450H Recombinant Human IL17RA Protein (Met1-Trp320), His-tagged, Biotinylated HEK293 His Met1-Trp320
Human IL17RA-449H Recombinant Human IL17RA Protein (Met1-Trp320), His-Fc-tagged, Biotinylated HEK293 His/Fc Met1-Trp320
Human IL17RA-4873H Recombinant Human IL17RA Protein, Fc/His-tagged Insect cells Fc/His 33-320 AA
Human IL17RA-2083HFL Recombinant Full Length Human IL17RA Protein, C-Flag-tagged Mammalian cells Flag
Human IL17RA-313H Recombinant Human IL17RA Protein, Fc-tagged HEK293 Fc 866
Human IL17RA-041H Recombinant Human IL17RA Protein, His-tagged E.coli His
Human IL17RA-208H Recombinant Human IL17RA protein, His-Avi-tagged HEK293 His-Avi It contains Leu33 - Trp320.
Human IL17RA-1167H-B Recombinant Human IL17RA Protein Pre-coupled Magnetic Beads HEK293
Human IL17RA-4162H Recombinant Human IL17RA Protein (Met1-Trp320), C-Fc tagged Mammalian cells C-Fc Met1-Trp320
Human IL17RA-312H Recombinant Human IL17RA Protein, His-tagged HEK293 His 866
Human IL17RA-299H Recombinant Human IL17RA protein, Fc-Avi-tagged HEK293 Fc-Avi It contains Leu33 - Trp320 .
Human IL17RA-0261H Active Recombinant Human IL17RA protein, His-tagged HEK293 His Leu33-Trp320
Human IL17RA-1167H Recombinant Human IL17RA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human IL17RA-175H Recombinant Human IL17RA Protein (Leu33-Trp320), C-6×His-tagged HEK293 C-6×His Leu33-Trp320
Human IL17RA-4161H Recombinant Human IL17RA Protein (Met1-Trp320), C-His tagged Mammalian cells C-His Met1-Trp320
Human CAB11561RH Rabbit Anti-Human Interleukin 17 Receptor A Monoclonal Antibody Rabbit N/A
Mouse Il17ra-4026M Active Recombinant Mouse Il17ra, His tagged HEK293 His Met 1-Trp 322
Mouse IL17RA-1328M Acitve Recombinant Mouse IL17RA protein(Met1-Trp322), hFc-tagged HEK293 C-hFc Met1-Trp322
Mouse Il17ra-1742M Recombinant Mouse Il17ra protein, His-tagged E.coli His Arg590-Trp848 (Accession # Q60943)
Mouse IL17RA-404M Recombinant Mouse IL17RA protein(Met1-Trp322), hFc-tagged HEK293 C-hFc Met1-Trp322
Mouse IL17RA-1070MCL Recombinant Mouse IL17RA cell lysate Human Cell N/A
Mouse Il17ra-1240M Recombinant Mouse Il17ra Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat Il17ra-7453R Active Recombinant Rat Il17ra, His-tagged Human Cell His
Rat IL17RA-1354R Acitve Recombinant Rat IL17RA protein(Met1-Pro320), hFc-tagged HEK293 C-hFc Met1-Pro320
Rat Il17ra-1743R Recombinant Rat Il17ra protein, His & T7-tagged E.coli His/T7 Gly617~Gly847 (Accession # D4A740)
Rat IL17RA-164R Recombinant Rat Il17ra, Fc tagged Human Cell His
Rat IL17RA-1441RCL Recombinant Rat IL17RA cell lysate Human Cell N/A
Cynomolgus Monkey IL17RA-8838C Recombinant Cynomolgus IL17RA, Fc tagged Human Cell Fc
Cynomolgus Monkey IL17RA-1252CCL Recombinant Cynomolgus IL17RA cell lysate Human Cell N/A
Rhesus IL17RA-2351R Recombinant Rhesus IL17RA protein(Met1-Trp320), hFc-tagged HEK293 C-hFc Met1-Trp320
Rhesus IL17RA-442R Active Recombinant Rhesus IL17RA Protein, His-tagged HEK293 His Met1-Trp320
Zebrafish IL17RA-5810Z Recombinant Zebrafish IL17RA Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

IL17RA involved in several pathways and played different roles in them. We selected most pathways IL17RA participated on our site, such as Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL17RA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionIFNA10;TNFRSF6B;CX3CR1;IL28RA;Il23a;IFNGR1;INHBC;IL8L2;IFN-a

IL17RA has several biochemical functions, for example, interleukin-17 receptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL17RA itself. We selected most functions IL17RA had, and list some proteins which have the same functions with IL17RA. You can find most of the proteins on our site.

Function Related Protein
interleukin-17 receptor activityIL17RC;IL17RE;IL17RB;IL17RD;IL17RA

IL17RA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL17RA here. Most of them are supplied by our site. Hope this information will be useful for your research of IL17RA.


  • Reviews
  • Q&As

Customer Reviews (3)

Write a review

    Effective in T-cell activation.


      Suitable for co-immunoprecipitation.


        High solubility.

        Q&As (10)

        Ask a question
        What experimental techniques are employed to investigate the interaction between IL17RA and various IL17 family members, and how is their binding specificity determined? 12/02/2022

        Surface plasmon resonance, co-immunoprecipitation, and mutagenesis studies reveal IL17RA's binding partners and affinity.

        Can you discuss the experimental designs used to examine the crosstalk between IL17RA signaling and other immune pathways, such as TNF-α or IFN-纬 pathways? 11/16/2020

        Cross-pathway signaling assays, gene expression profiling, and functional rescue experiments unveil IL17RA's interaction networks.

        What strategies are utilized to explore the contribution of IL17RA to tissue remodeling processes, such as angiogenesis and fibrosis? 11/08/2020

        Angiogenesis assays, fibroblast activation assays, and tissue remodeling models illuminate IL17RA's role in tissue repair.

        How is the potential of IL17RA as a therapeutic target evaluated in experimental settings, and what challenges exist in translating these findings to clinical applications? 03/15/2020

        Animal models, pharmacological interventions, and toxicity assessments evaluate IL17RA-targeted therapies and translational challenges.

        How do researchers study the involvement of IL17RA in autoimmune disorders through patient samples, and what insights have been gained? 12/26/2019

        Patient cohorts, clinical data analysis, and immune profiling provide insights into IL17RA's relevance in autoimmune diseases.

        How do researchers study the role of IL17RA in the regulation of immune cell recruitment and infiltration in inflammatory tissues? 12/13/2018

        Flow cytometry, in vivo imaging, and chemotaxis assays characterize immune cell responses guided by IL17RA activation.

        Can you elaborate on the methods used to dissect the intracellular signaling pathways triggered by IL17RA activation, especially in the context of autoimmune diseases? 04/28/2018

        Phosphorylation assays, gene expression analysis, and knockout models dissect IL17RA-mediated signaling cascades.

        Could you explain the experimental approaches employed to assess the impact of IL17RA inhibition on chronic inflammatory diseases in preclinical models? 01/10/2018

        Disease models, antibody-based treatments, and inflammatory biomarker assessments elucidate IL17RA's therapeutic potential.

        What molecular methods are employed to understand the genetic and epigenetic regulation of IL17RA expression in immune cells? 07/22/2017

        ChIP-sequencing, promoter analysis, and epigenetic modification studies uncover IL17RA gene regulation mechanisms.

        What techniques are used to investigate the role of IL17RA in maintaining epithelial barrier integrity and preventing microbial invasion? 03/06/2017

        Epithelial barrier assays, microbiome analysis, and infection models decipher IL17RA's role in mucosal defense.

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