IL17RA
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Official Full Name
interleukin 17 receptor A -
Overview
Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the;maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin;17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A.;Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as;rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. -
Synonyms
CD217;IL17R;CANDF5;CDw217;IL-17RA;hIL-17R;interleukin-17 receptor A;IL-17 receptor A;Brodalumab;1174395-19-7;Ixekizumab;1143503-69-8
Recombinant Proteins
- Mouse
- Human
- Rat
- Rhesus macaque
- Zebrafish
- Cynomolgus
- HEK293
- Human Cells
- E.coli
- Mammalian Cells
- Rabbit
- Insect cells
- His
- Fc
- Avi
- T7
- Non
- DDK
- Myc
- Flag
Involved Pathway
IL17RA involved in several pathways and played different roles in them. We selected most pathways IL17RA participated on our site, such as Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL17RA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cytokine-cytokine receptor interaction | CCL21,Ccl12,IFNA7,CCR3,TNFRSF25,FLT3,BMPR2A,TNFRSF14,Il23a; Il12b,CCL17 |
Protein Function
IL17RA has several biochemical functions, for example, interleukin-17 receptor activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL17RA itself. We selected most functions IL17RA had, and list some proteins which have the same functions with IL17RA. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| interleukin-17 receptor activity | IL17RD,IL17RC,IL17RB,IL17RE |
| protein binding | TEX14,CXADR,RALB,CST2,LRP1,IGFN1,CENPL,MALT1,DGKZ,PDE4A |
Interacting Protein
IL17RA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL17RA here. Most of them are supplied by our site. Hope this information will be useful for your research of IL17RA.
IL17RE
Resources
Research Area
Multiple Sclerosis and Myelin Related MoleculesCD Antigen (Helper T Cells)
T Follicular Helper (Tfh) Cells
Th17 Cells
Th2 Cells
Th9 Cells
IL-17 Family Receptors
Related Services
Related Products
References
