Recombinant Active Mouse IL33 Protein, His-tagged(C-ter)
Cat.No. : | Il33-192M |
Product Overview : | Recombinant Active Mouse IL33 Protein with His tag (C-ter) was expressed in E. coli. |
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Description : | The protein encoded by this gene is a cytokine that binds to the IL1RL1/ST2 receptor. The encoded protein is involved in the maturation of Th2 cells and the activation of mast cells, basophils, eosinophils and natural killer cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015] |
Source : | E. coli |
Species : | Mouse |
Tag : | His |
Form : | Powder |
Bio-activity : | Determined by its ability to induce proliferation in D10.G4.1 cells. The ED50 for this effect is < 40 pg/ml. The specific activity of recombinant mouse IL-33 is > 2 x 10^7 IU/mg. |
AA Sequence : | MSIQGTSLLTQSPASLSTYNDQSVS FVLENGCYVINVDDSGKDQEQDQVL LRYYESPCPASQSGDGVDGKKLMVN MSPIKDTDIWLHANDKDYSVELQRG DVSPPEQAFFVLHKKSSDFVSFECK NLPGTYIGVKDNQLALVEEKDESCN NIMFKLSKI |
Endotoxin : | Endotoxin level is less than 0.1 EU/μg of the protein, as determined by the LAL test. |
Purity : | > 98% (by SDS-PAGE) |
Applications : | SDS-PAGE |
Notes : | For laboratory research only, not for drug, diagnostic or other use. |
Storage : | Lyophilized protein should be stored at -20°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
Storage Buffer : | PBS (pH 7.4) |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
Gene Name : | Il33 interleukin 33 [ Mus musculus ] |
Official Symbol : | Il33 |
Synonyms : | IL33; interleukin 33; interleukin-33; nuclear factor from high endothelial venules; Il-33; Il1f11; NF-HEV; 9230117N10Rik; |
Gene ID : | 77125 |
mRNA Refseq : | NM_001164724 |
Protein Refseq : | NP_001158196 |
Products Types
◆ Recombinant Protein | ||
IL33-643D | Recombinant Dog IL33 protein(102-263aa), His-tagged | +Inquiry |
IL33-095I | Active Recombinant Human IL33 Protein (159 aa) | +Inquiry |
Il33-3521M | Recombinant Mouse Il33 Protein | +Inquiry |
IL33-4211D | Recombinant Dog IL33 protein(102-263aa), His-tagged | +Inquiry |
IL33-175M | Active Recombinant Mouse IL33 Protein | +Inquiry |
◆ Lysates | ||
IL33-5226HCL | Recombinant Human IL33 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewGood solubility and is easy to operate and purify.
Effectively mimics the function of the target protein in vitro.
IL33 has a wide range of applications in the field of scientific research and is suitable for a variety of experimental design and research purposes.
Q&As (6)
Ask a questionIt can be used to detect immune cells such as macrophages and dendritic cells.
This protein applied in immunology, drug research, life science and other fields.
Regulates the activity of immune cells by binding to receptors to stimulate the production of inflammatory factors such as interferon and TNF-α.
IL33 can also be used to treat a variety of inflammatory diseases, such as inflammatory bowel disease, psoriasis and so on.
The preparation of IL33 requires first cloning the IL33 gene into the expression vector, and then the expression vector is expressed and purified in the cell culture medium.
Treating asthma with recombinant IL33 takes several weeks to several months to be effective, depending on the severity of the condition and the individual patient.
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