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Official Full Name interleukin 33
Background IL33 (MIM 608678) is a member of the IL1 (see MIM 147760) family that potently drives production of T helper-2 (Th2)-associated cytokines (e.g., IL4; MIM 147780). IL33 is a ligand for IL33R (IL1RL1; MIM 601203), an IL1 family receptor that is selectively expressed on Th2 cells and mast cells (summary by Yagami et al., 2010 [PubMed 20926795]).[supplied by OMIM, Jan 2011]
Synonyms IL33; interleukin 33; DVS27; IL1F11; NF-HEV; NFEHEV; C9orf26; interleukin-33; IL-33; IL-1F11; DVS27-related protein; interleukin-1 family member 11; nuclear factor for high endothelial venules; nuclear factor from high endothelial venules;
    • Species :
    • Canine
    • Cynomolgus
    • Human
    • Mouse
    • Rat
    • Source :
    • CHO
    • E. coli
    • E.coli
    • HEK293
    • Human
    • Human Cells
    • Mammalian Cell
    • Mouse
    • Wheat Germ
    • Tag :
    • Fc
    • Flag
    • GST
    • His
    • His-Avi
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IL33-066H Recombinant Human IL33 Protein E. coli
    Human IL33-151H Recombinant Human IL33 Protein, His-tagged Human Cells His
    Human IL33-301497H Recombinant Human IL33 protein, GST-tagged E.coli GST
    Human CAB11566MH Mouse Anti-Human Interleukin-33 Monoclonal Antibody Mouse N/A
    Human IL33-121H Recombinant Human Interleukin 33, MIgG2a Fc-tagged CHO Fc
    Human IL33-122H Recombinant Human Interleukin 33, HIgG1 Fc-tagged, mutant CHO Fc
    Human IL33-124H Recombinant Human Interleukin 33, HIgG1 Fc-tagged CHO Fc
    Human IL33-138H Recombinant Human IL33 protein E.coli N/A
    Human IL33-215H Recombinant Human IL33 protein E.coli N/A
    Human IL33-29791TH Recombinant Human IL33 protein, FLAG-tagged HEK293 Flag
    Human IL33-310H Recombinant Human IL33 protein, His-tagged HEK293 His
    Human IL33-320H Recombinant Human Interleukin 33 E.coli N/A
    Human IL33-322H Recombinant Human IL33, His-tagged E.coli His
    Human IL33-32H Recombinant Human IL33 protein, His-tagged E.coli His
    Human IL33-4337HG GMP Recombinant Human IL33 protein E.coli N/A
    Human IL33-448H Recombinant Human Interleukin 33, His-tagged Human His
    Human IL33-5188H Recombinant Human IL33 Protein, GST-tagged Wheat Germ GST
    Human IL33-5226HCL Recombinant Human IL33 293 Cell Lysate HEK293 N/A
    Human IL33-58H Recombinant Human Interleukin 33 E.coli N/A
    Human IL33-59H Recombinant Human IL33, His-tagged E.coli His
    Human IL33-760H Recombinant Human IL33 protein, His-Avi-tagged HEK293 His-Avi
    Mouse IL33-120M Recombinant Mouse Interleukin 33, MIgG2a Fc-tagged, mutant CHO Fc
    Mouse IL33-130M Recombinant Mouse Interleukin 33, MIgG2a Fc-tagged CHO Fc
    Mouse Il33-157M Recombinant Mouse Il33 Protein E.coli
    Mouse Il33-158M Recombinant Mouse Il33 Protein E.coli
    Mouse IL33-1917M Recombinant Mouse IL33 Protein E.coli N/A
    Mouse Il33-2061M Recombinant Mouse Il33 protein, GST-tagged E.coli GST
    Mouse Il33-207M Recombinant Mouse Il33 protein E.coli N/A
    Mouse Il33-3521M Recombinant Mouse Il33 Protein E. coli
    Mouse Il33-358M Recombinant Mouse Il33, His-tagged E.coli His
    Mouse Il33-5186M Recombinant Mouse Il33 Protein E.coli N/A
    Mouse IL33-637M Recombinant Mouse interleukin 33, His-tagged E.coli His
    Mouse Il33-7419M Recombinant Mouse Il33 Protein, His-tagged E.coli His
    Rat Il33-286R Recombinant Rat Interleukin 33 E.coli N/A
    Rat IL33-3045R Recombinant Rat IL33 Protein Mammalian Cell His
    Rat Il33-50R Recombinant Rat Il33 protein, His-tagged E.coli His
    Rat Il33-583R Recombinant Rat Il33 protein E.coli N/A
    Cynomolgus IL33-17C Recombinant Cynomolgus IL33 protein (Ser112-Ile270) E. coli
    Canine IL33-1034C Recombinant Canine IL33 Protein E.coli N/A

    Il33 involved in several pathways and played different roles in them. We selected most pathways Il33 participated on our site, such as Cytosolic DNA-sensing pathway, Influenza A, which may be useful for your reference. Also, other proteins which involved in the same pathway with Il33 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytosolic DNA-sensing pathway IFNA17; CCL4; RIPK1; NFKBIA; Ifna15; CXCL10; IFNA5; NFKBIB; IL1B; POLR3GL
    Influenza A TNFRSF10D; HLA-DPB1; PML; Ifna11; PIK3R3; Ccl12; IL18; MAPK8; NLRP3; NXT1

    Il33 has several biochemical functions, for example, cytokine activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Il33 itself. We selected most functions Il33 had, and list some proteins which have the same functions with Il33. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activity IFNA14; GDF10B; VEGFA; GDF10; TXLNA; IFNA1; Ccl12; GDF6B; TNFSF4; GDF5
    protein binding HDAC7A; GPSM2; BAX; WNT3A; HOOK2; DUSP2; ZRANB1; RAB33B; CD244; BBS12

    Il33 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Il33 here. Most of them are supplied by our site. Hope this information will be useful for your research of Il33.


    Li, C; Mu, R; et al. Genetic variant in IL33 is associated with susceptibility to rheumatoid arthritis. ARTHRITIS RESEARCH & THERAPY 16:-(2014).
    Tordesillas, L; Gomez-Casado, C; et al. Transport of Pru p 3 across gastrointestinal epithelium - an essential step towards the induction of food allergy?. CLINICAL AND EXPERIMENTAL ALLERGY 43:1374-1383(2013).


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