Il33

  • Official Full Name

    interleukin 33

  • Overview

    IL33 (MIM 608678) is a member of the IL1 (see MIM 147760) family that potently drives production of T helper-2 (Th2)-associated cytokines (e.g., IL4; MIM 147780). IL33 is a ligand for IL33R (IL1RL1; MIM 601203), an IL1 family receptor that is selectively expressed on Th2 cells and mast cells (summary by Yagami et al., 2010 [PubMed 20926795]).[supplied by OMIM, Jan 2011]
  • Synonyms

    IL33; interleukin 33; DVS27; IL1F11; NF-HEV; NFEHEV; C9orf26; interleukin-33; IL-33; IL-1F11; DVS27-related protein; interleukin-1 family member 11; nuclear factor for high endothelial venules; nuclear factor from high endothelial venules;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • GMP Proteins
  • Antibody
  • Protein Pre-coupled Magnetic Beads
  • Canine
  • Cynomolgus
  • Human
  • Mouse
  • Pig
  • Rat
  • CHO
  • E. coli
  • E.coli
  • HEK293
  • Human
  • Human Cells
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mouse
  • Wheat Germ
  • Avi
  • C
  • His
  • Fc
  • Flag
  • GST
  • His (Fc)
  • His(C
  • ter)
  • N/A
  • N
  • Tag Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IL33-122H Active Recombinant Human Interleukin 33, HIgG1 Fc-tagged, mutant CHO Fc
Human IL33-124H Active Recombinant Human Interleukin 33, HIgG1 Fc-tagged CHO Fc
Human IL33-121H Active Recombinant Human Interleukin 33, MIgG2a Fc-tagged CHO Fc
Human IL33-215H Active Recombinant Human IL33 protein E.coli N/A
Human IL33-2218H Active Recombinant Human IL33 protein, His-tagged HEK293 His
Human IL33-322H Recombinant Human IL33, His-tagged E.coli His
Human IL33-29791TH Active Recombinant Human IL33 protein, FLAG-tagged HEK293 Flag
Human IL33-448H Recombinant Human Interleukin 33, His-tagged Human His
Human IL33-59H Recombinant Human IL33, His-tagged E.coli His
Human IL33-320H Recombinant Human Interleukin 33 E.coli N/A
Human IL33-58H Recombinant Human Interleukin 33 E.coli N/A
Human IL33-32H Recombinant Human IL33 protein, His-tagged E.coli His
Human IL33-138H Recombinant Human IL33 protein E.coli N/A
Human IL33-5226HCL Recombinant Human IL33 293 Cell Lysate HEK293 N/A
Human IL33-301497H Recombinant Human IL33 protein, GST-tagged E.coli GST
Human IL33-4337HG Active GMP Recombinant Human IL33 protein E.coli N/A
Human IL33-151H Recombinant Human IL33 Protein, His-tagged Human Cells His
Human IL33-760H Recombinant Human IL33 protein, His-Avi-tagged HEK293 His-Avi
Human IL33-45H Recombinant Human IL33 Protein, N-Avi tagged, Biotinylated E.coli N-Avi
Human IL33-5188H Recombinant Human IL33 Protein, GST-tagged Wheat Germ GST
Human IL33-212H Recombinant Human IL33 Protein, His-tagged E.coli His
Human IL33-066H Active Recombinant Human IL33 Protein E. coli
Human IL33-191H Recombinant Active Human IL33 Protein, His-tagged(C-ter) E.coli His(C-ter)
Human IL33-2313H Recombinant Human IL33 Protein, His-tagged E.coli N-His
Human IL33-520HFL Recombinant Full Length Human IL33 Protein, N-His-tagged E.coli His
Human IL33-356I Active Recombinant Human IL33 Protein (159 aa) E.coli
Human IL33-110H Recombinant Human IL33 Protein E.coli
Human IL33-5783HF Recombinant Full Length Human IL33 Protein, GST-tagged In Vitro Cell Free System GST
Human IL33-2897H Recombinant Human IL33 Protein (Ser112-Thr270), His tagged E.coli His
Human IL33-2572H Active Recombinant Human IL33 protein E.coli N/A
Human IL33-218H Recombinant Human IL33 Protein, Avi-tagged E.coli Avi
Human IL33-174H Active Recombinant Human IL33 Protein E.coli
Human IL33-0290H Active Recombinant Human IL33 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi
Human IL33-310H Recombinant Human IL33 protein, His-tagged HEK293 His
Human IL33-312H Active Recombinant Human IL33 Protein (Ser112-Thr270), C-His tagged, Animal-free, Carrier-free E.coli C-His
Human IL33-165H Recombinant Human IL33 Protein, Avi-tagged E.coli Avi
Human IL33-166H Recombinant Human IL33 Protein E.coli
Human IL33-095I Active Recombinant Human IL33 Protein (159 aa) E.coli
Human IL33-486H Active Recombinant Human IL33 Protein E.coli Tag Free
Human CAB11566MH Mouse Anti-Human Interleukin-33 Monoclonal Antibody Mouse N/A
Mouse Il33-358M Active Recombinant Mouse Il33, His-tagged E.coli His
Mouse IL33-130M Active Recombinant Mouse Interleukin 33, MIgG2a Fc-tagged CHO Fc
Mouse IL33-120M Active Recombinant Mouse Interleukin 33, MIgG2a Fc-tagged, mutant CHO Fc
Mouse Il33-01M Active Recombinant Mouse Il33 Protein, His-Tagged E.coli His
Mouse Il33-207M Recombinant Mouse Il33 protein E.coli N/A
Mouse IL33-637M Recombinant Mouse interleukin 33, His-tagged E.coli His
Mouse Il33-2061M Recombinant Mouse Il33 protein, GST-tagged E.coli GST
Mouse Il33-5186M Active Recombinant Mouse Il33 Protein E.coli N/A
Mouse Il33-3521M Recombinant Mouse Il33 Protein E. coli
Mouse IL33-1917M Recombinant Mouse IL33 Protein E.coli N/A
Mouse Il33-7419M Recombinant Mouse Il33 Protein, His-tagged E.coli His
Mouse Il33-026I Active Recombinant Mouse Il33 Protein (158 aa) E.coli
Mouse Il33-295M Active Recombinant Mouse Il33 Protein (Ser109-Ile266), C-His tagged, Animal-free, Carrier-free E.coli C-His
Mouse Il33-1679M Recombinant Mouse Il33 Protein, His-tagged E.coli N-His
Mouse IL33-1019M Recombinant Mouse IL33 protein, His-tagged HEK293 His
Mouse Il33-157M Recombinant Mouse Il33 Protein E.coli
Mouse IL33-163M Recombinant Mouse IL33 Protein E.coli
Mouse IL33-2221M Recombinant Mouse IL33 protein, His-tagged HEK293 His
Mouse IL33-0289M Recombinant Mouse IL33 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi
Mouse Il33-158M Active Recombinant Mouse Il33 Protein E.coli
Mouse Il33-192M Recombinant Active Mouse IL33 Protein, His-tagged(C-ter) E.coli His(C-ter)
Mouse IL33-175M Active Recombinant Mouse IL33 Protein E.coli
Rat Il33-583R Recombinant Rat Il33 protein E.coli N/A
Rat Il33-286R Recombinant Rat Interleukin 33 E.coli N/A
Rat IL33-3045R Recombinant Rat IL33 Protein Mammalian Cell His
Rat Il33-50R Recombinant Rat Il33 protein, His-tagged E.coli His
Rat IL33-2700R Recombinant Rat IL33 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat IL33-2700R-B Recombinant Rat IL33 Protein Pre-coupled Magnetic Beads HEK293
Canine IL33-1034C Active Recombinant Canine IL33 protein E.coli N/A
Cynomolgus IL33-0291C Active Recombinant Cynomolgus IL33 protein, His-tagged HEK293 His
Cynomolgus IL33-164C Recombinant Cynomolgus IL33 Protein E.coli
Cynomolgus IL33-17C Recombinant Cynomolgus IL33 protein E.coli N/A
Pig IL33-3103P Recombinant Pig IL33 protein, GST-tagged E.coli GST
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Il33 Related Articles
  • Il33 Related Gene Family
  • Il33 Related Research Area

Il33 involved in several pathways and played different roles in them. We selected most pathways Il33 participated on our site, such as Cytosolic DNA-sensing pathway, Influenza A, which may be useful for your reference. Also, other proteins which involved in the same pathway with Il33 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytosolic DNA-sensing pathwayRELA;AIM2;IFNA16;CCL4L2;TBK1;MB21D1;IFNPHI1;IFNA14;IFNB1
Influenza ALOC100033925;TNFRSF10A;FURIN;TNFRSF10B;BLB1;GSK3B;IL8L2;Ifna11;IRF9

Il33 has several biochemical functions, for example, cytokine activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Il33 itself. We selected most functions Il33 had, and list some proteins which have the same functions with Il33. You can find most of the proteins on our site.

Function Related Protein
cytokine activityVSTM1;IL22;IL3;FAM3C;NAMPT;GPI;IL17A/F2;CSF1B;IFNB1
protein bindingTYR;PACSIN3;NCBP1;UNC119;HER5;ATXN1L;CD164;TXNRD3;EXOSC2

Il33 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Il33 here. Most of them are supplied by our site. Hope this information will be useful for your research of Il33.

HIST1H2AG; IL1RL1; CRMP1; HIST1H2BC

Li, C; Mu, R; et al. Genetic variant in IL33 is associated with susceptibility to rheumatoid arthritis. ARTHRITIS RESEARCH & THERAPY 16:-(2014).
Tordesillas, L; Gomez-Casado, C; et al. Transport of Pru p 3 across gastrointestinal epithelium - an essential step towards the induction of food allergy?. CLINICAL AND EXPERIMENTAL ALLERGY 43:1374-1383(2013).
IL
  • Q&As
  • Reviews

Q&As (6)

Ask a question
Which immune cells can recombinant IL33 be used to detect? 05/28/2022

It can be used to detect immune cells such as macrophages and dendritic cells.

In what research fields can recombinant IL33 be applied? 09/24/2020

This protein applied in immunology, drug research, life science and other fields.

What is the action mechanism of IL33? 08/09/2020

Regulates the activity of immune cells by binding to receptors to stimulate the production of inflammatory factors such as interferon and TNF-α.

Besides treating asthma and hay fever, what other diseases can be treated with IL33? 07/28/2019

IL33 can also be used to treat a variety of inflammatory diseases, such as inflammatory bowel disease, psoriasis and so on.

How to prepare IL33? 03/25/2019

The preparation of IL33 requires first cloning the IL33 gene into the expression vector, and then the expression vector is expressed and purified in the cell culture medium.

How long does it take to treat asthma with IL33? 01/10/2019

Treating asthma with recombinant IL33 takes several weeks to several months to be effective, depending on the severity of the condition and the individual patient.

Customer Reviews (3)

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Reviews
10/16/2021

    Good solubility and is easy to operate and purify.

    05/03/2021

      Effectively mimics the function of the target protein in vitro.

      03/18/2020

        IL33 has a wide range of applications in the field of scientific research and is suitable for a variety of experimental design and research purposes.

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