Recombinant Cynomolgus Monkey CD59 Protein Pre-coupled Magnetic Beads

• Cat.No.: CD59-140C-B
• Product Overview: The Recombnant protein was conjugated to magnetic beads. This ready-to-use, pre-coupled magnetic beads are in uniform particle size and narrow size distribution with large surface area, which is conducive to convenient and fast capture target molecules with high specificity and achieve magnetic separation. This product can be equipped with automation equipment for high-throughput operations.

Specification

• Source: HEK293
• Species: Cynomolgus Monkey
• Form: Solution
• Particle size: ~2 μm
• Beads Surface: Hydrophilic
• Capacity: > 200 pmol rabbit IgG/ mg beads
• Applications: Immunoassay, In vitro diagnostics, cell sorting, Immunoprecipitation/Co-precipitation, Protein/antibody separation and purification.
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions.
• Storage: 2-8℃. Do not to freeze thaw the Beads
• Concentration: 10mg beads/mL
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: CD59 CD59 glycoprotein [ Macaca fascicularis (crab-eating macaque) ]
• Official Symbol: CD59
• Synonyms: CD59; MACIF; MAC-IP; Protectin; QmoA-10351; QnpA-17056; CD59 antigen p18-20 allele A; CD59 antigen p18-20 allele B; MAC-inhibitory protein; Membrane attack complex inhibition factor
• Gene ID: 101867071
• mRNA Refseq: NM_001283527
• Protein Refseq: NP_001270456
• UniProt ID: G7PQF7

Reviews

05/09/2022

The quality is very high and the reliability is very helpful for our research results.

03/17/2021

There are no doping impurities, the experimental effect is very good, and I will recommend it to other students.

01/13/2021

Easy to operate and cost-effective.

Q&As

How to explain the role of CD59 in hemolytic disease?

In hemolytic diseases, the deficiency or dysfunction of CD59 may lead to excessive lysis of red blood cells because the formation of the complement C5b-9 complex cannot be effectively prevented.

Are there differences in CD59 expression levels in different types of cells?

Yes, the expression level of CD59 can vary in different cell types. In general, it is expressed higher in blood cells and some tumor cells.

What are some of the technical challenges that laboratories may encounter when researching CD59?

When researching CD59, laboratories may encounter technical challenges such as selecting the appropriate assay, ensuring the quality and consistency of samples, and the complexity of interpreting results. In addition, CD59 expression variations in different cell types and experimental conditions need to be considered.

What diseases are associated with aberrant expression of CD59?

Aberrant expression of CD59 has been associated with a variety of diseases, including but not limited to hemolytic diseases, certain types of cancer, and autoimmune diseases.

How can I measure CD59 expression in the laboratory?

CD59 expression can be detected using flow cytometry, immunofluorescence staining, or western blotting.

Is there a current treatment for CD59?

The current treatment for CD59 is still in the research stage, and there is no drug approved for clinical use. However, some studies are exploring the use of gene therapy or antibody therapy to modulate CD59 expression or function.