Recombinant Full Length Human BACH1 Protein, C-Flag-tagged

• Cat.No.: BACH1-254HFL
• Product Overview: Recombinant Full Length Human BACH1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 81.8 kDa
• AA Sequence: MSLSENSVFAYESSVHSTNVLLSLN DQRKKDVLCDVTIFVEGQRFRAHRS VLAACSSYFHSRIVGQADGE LNITLPEEVTVKGFEPLIQFAYTAK LILSKENVDEVCKCVEFLSVHNIEE SCFQFLKFKFLDSTADQQEC PRKKCFSSHCQKTDLKLSLLDQRDL ETDEVEEFLENKNVQTPQCKLRRYQ GNAKASPPLQDSASQTYESM CLEKDAALALPSLCPKYRKFQKAFG TDRVRTGESSVKDIHASVQPNERSE NECLGGVPECRDLQVMLKCD ESKLAMEPEETKKDPASQCPTEKSE VTPFPHNSSIDPHGLYSLSLLHTYD QYGDLNFAGMQNTTVLTEKP LSGTDVQEKTFGESQDLPLKSDLGT REDSSVASSDRSSVEREVAEHLAKG FWSDICSTDTPCQMQLSPAV AKDGSEQISQKRSECPWLGIRISES PEPGQRTFTTLSSVNCPFISTLSTE GCSSNLEIGNDDYVSEPQQE PCPYACVISLGDDSETDTEGDSESC SAREQECEVKLPFNAQRIISLSRND FQSLLKMHKLTPEQLDCIHD IRRRSKNRIAAQRCRKRKLDCIQNL ESEIEKLQSEKESLLKERDHILSTL GETKQNLTGLCQKVCKEAAL SQEQIQILAKYSAADCPLSFLISEK DKSTPDGELALPSIFSLSDRPPAVL PPCARGNSEPGYARGQESQQ
  MSTATSEQAGPAEQCRQSGGISDFC QQMTDKCTTDETRTRPLEQKLISEE DLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Transcription Factors

Gene Information

• Gene Name: BACH1 BTB domain and CNC homolog 1 [ Homo sapiens (human) ]
• Official Symbol: BACH1
• Synonyms: BACH-1; BTBD24
• Gene ID: 571
• mRNA Refseq: NM_001186.4
• Protein Refseq: NP_001177.1
• MIM: 602751
• UniProt ID: O14867