Recombinant Full Length Human CASP3 Protein, GST-tagged
Cat.No. : | CASP3-668HF |
Product Overview : | Recombinant full length Human CASP3(1 a.a. - 277 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Form : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Molecular Mass : | 56.21 kDa |
Protein Length : | 277 amino acids |
AA Sequence : | MENTENSVDS KSIKNLEPKI IHGSESMDSG ISLDNSYKMD YPEMGLCIII NNKNFHKSTG MTSRSGTDVD AANLRETFRN LKYEVRNKND LTREEIVELM RDVSKEDHSK RSSFVCVLLS HGEEGIIFGT NGPVDLKKIT NFFRGDRCRS LTGKPKLFII QACRGTELDC GIETDSGVDD DMACHKIPVE ADFLYAYSTA PGYYSWRNSK DGSWFIQSLC AMLKQYADKL EFMHILTRVN RKVATEFESF SFDATFHAKK QIPCIVSILT KELYFYH |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Gene Name : | CASP3 caspase 3, apoptosis-related cysteine peptidase [ Homo sapiens ] |
Official Symbol : | CASP3 |
Synonyms : | CASP3; caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis related cysteine protease; caspase-3; apopain; CPP32; CPP32B; Yama; CASP-3; CPP-32; procaspase3; protein Yama; PARP cleavage protease; cysteine protease CPP32; SREBP cleavage activity 1; caspase 3, apoptosis-related cysteine protease; SCA-1 |
Gene ID : | 836 |
mRNA Refseq : | NM_004346 |
Protein Refseq : | NP_004337 |
MIM : | 600636 |
UniProt ID : | P42574 |
Products Types
◆ Recombinant Protein | ||
CASP3-0595H | Recombinant Human CASP3 Protein (M1-H277), His/Strep tagged | +Inquiry |
CASP3-0421H | Recombinant Human CASP3 Protein, GST-Tagged | +Inquiry |
CASP3-188H | Recombinant Human CASP3 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
CASP3-110C | Recombinant Cynomolgus Monkey CASP3 Protein, His (Fc)-Avi-tagged | +Inquiry |
CASP3-623C | Recombinant Cattle CASP3 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CASP3-7839HCL | Recombinant Human CASP3 293 Cell Lysate | +Inquiry |
CASP3-7838HCL | Recombinant Human CASP3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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