Recombinant Mouse Casp3 protein, His-tagged
Cat.No. : | Casp3-623M |
Product Overview : | Recombinant Mouse Casp3 aa. (Ser29~Asp175) fused with N-terminal His tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a protein that belongs to a highly conserved family of cysteinyl aspartate-specific proteases that function as essential regulators of programmed cell death through apoptosis. Members of this family contain an N-terminal pro-domain and require cleavage at specific aspartate residues to become mature. The protein encoded by this gene belongs to a subgroup of cysteinyl aspartate-specific proteases that are activated by initiator caspases and that perform the proteolytic cleavage of apoptotic target proteins. Mice defective for this gene exhibit a variety of phenotypes including reduced neuronal apoptosis resulting in hyperplasias, hearing loss, attenuated osteogenic differentiation of bone marrow stromal stem cells, and pre- and post-natal lethality. Alternative splicing results in multiple transcript variants. |
Source : | E. coli |
Species : | Mouse |
Tag : | His |
Form : | Freeze-dried powder |
Molecular Mass : | 20kDa as determined by SDS-PAGE reducing conditions. |
Protein length : | Ser29~Asp175 |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | >95% |
Characteristic : | The isoelectric point is 6.8. |
Applications : | SDS-PAGE; WB; ELISA; IP; CoIP; Purification; Amine Reactive Labeling |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Concentration : | 200µg/mL |
Storage buffer : | 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300. |
Reconstitution : | Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex |
Gene Name : | Casp3 caspase 3 [ Mus musculus (house mouse) ] |
Official Symbol : | Casp3 |
Synonyms : | Casp3; caspase 3; CC3; AC-3; Lice; Yama; mldy; CPP32; SCA-1; CASP-3; CPP-32; Caspase-3; A830040C14Rik; caspase-3; SREBP cleavage activity 1; apopain; caspase 3, apoptosis related cysteine protease; cysteine protease CPP32; protein Yama |
Gene ID : | 12367 |
mRNA Refseq : | NM_001284409.1 |
Protein Refseq : | NP_001271338.1 |
UniProt ID : | P70677 |
Products Types
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CASP3-110C | Recombinant Cynomolgus Monkey CASP3 Protein, His (Fc)-Avi-tagged | +Inquiry |
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◆ Lysates | ||
CASP3-7838HCL | Recombinant Human CASP3 293 Cell Lysate | +Inquiry |
CASP3-7839HCL | Recombinant Human CASP3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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