Recombinant Full Length Human G6PC1 Protein, C-Myc/DDK-tagged

Species :	Human
Source :	HEK293
Tag :	DDK&Myc
Description :	Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1). This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.
Form :	100 mM KH2PO4,pH 7.4, 400 mM KCl, 500 mM NaCl,0.025% Triton x-100.
Molecular Mass :	40.5 kDa
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining.
Stability :	Stable for at least 2 years from receipt of products under proper storage and handling conditions.
Storage :	Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration :	0.13ug/ul
Full Length :	Full L.

Gene Name	G6PC1 glucose-6-phosphatase catalytic subunit 1 [ Homo sapiens (human) ]
Official Symbol	G6PC1
Synonyms	G6PC; G6PT; GSD1; GSD1a; G6Pase
Gene ID	2538
mRNA Refseq	NM_000151.4
Protein Refseq	NP_000142.2
MIM	613742
UniProt ID	P35575