Recombinant Full Length Human G6PC1 Protein, C-Myc/DDK-tagged

• Cat.No.: G6PC1-25HFL
• Product Overview: Recombinant Full Length Human G6PC1 Protein, fused to Myc/DDK-tag at C-terminus, was expressed in HEK293T.

Specification

• Description: Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1). This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.
• Source: HEK293T
• Species: Human
• Tag: Myc/DDK
• Form: 100 mM KH2PO4,pH 7.4, 400 mM KCl, 500 mM NaCl,0.025% Triton x-100.
• Molecular Mass: 40.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for at least 2 years from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 0.13ug/ul

Gene Information

• Gene Name: G6PC1 glucose-6-phosphatase catalytic subunit 1 [ Homo sapiens (human) ]
• Official Symbol: G6PC1
• Synonyms: G6PC; G6PT; GSD1; GSD1a; G6Pase
• Gene ID: 2538
• mRNA Refseq: NM_000151.4
• Protein Refseq: NP_000142.2
• MIM: 613742
• UniProt ID: P35575