| Description : |
This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants. |
| Source : |
In Vitro Cell Free System |
| Species : |
Human |
| Form : |
Liquid |
| Molecular Mass : |
89.250kDa |
| Protein Length : |
575 amino acids |
| AA Sequence : |
MGLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLS LVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYF PVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELV KKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVA FAVVGACQALGLRDVHLALSEDHAWSWLYLKGSYMRCDRK MEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHL ERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYY RDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNY CREDEEIYKEFFEVANDVIPNLLKEAASLLEAGEERPGEQ SQGTQSQGSALQDPECFAHLLRFYDGICKWEEGSPTPVLH VGWATFLVQSLGRFEGQVRQKVRIVSREAEAAEAEEPWGE EAREGRRRGPRRESKPEEPPPPKKPALDKGLGTGQGAVSG PPRKPPGTVAGTARGPEGGSTAQVPAPAASPPPEGPVLTF QSEKMKGMKELLVATKINSSAIKLQLTAQSQVQMKKQKVS TPSDYTLSFLKRQRKGL |
| Purity : |
Proprietary Purification |
| Storage : |
Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles. |
| Storage Buffer : |
pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione. |
