| Description : |
This gene encodes menin, a tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. Menin is a scaffold protein that functions in histone modification and epigenetic gene regulation. It is thought to regulate several pathways and processes by altering chromatin structure through the modification of histones. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
67.3 kDa |
| AA Sequence : |
MGLKAAQKTLFPLRSIDDVVRLFAA ELGREEPDLVLLSLVLGFVEHFLAV NRVIPTNVPELTFQPSPAPDPPGGL TYFPVADLSIIAALYARFTAQIRGA VDLSLYPREGGVSSRELVKKVSDVI WNSLSRSYFKDRAHIQSLFSFITGT KLDSSGVAFAVVGACQALGLRDVHL ALSEDHAWVVFGPNGEQTAEVTWHG KGNEDRRGQTVNAGVAERSWLYLKG SYMRCDRKMEVAFMVCAINPSIDLH TDSLELLQLQQKLLWLLYDLGHLER YPMALGNLADLEELEPTPGRPDPLT LYHKGIASAKTYYRDEHIYPYMYLA GYHCRNRNVREALQAWADTATVIQD YNYCREDEEIYKEFFEVANDVIPNL LKEAASLLEAGEERPGEQSQGTQSQ GSALQDPECFAHLLRFYDGICKWEE GSPTPVLHVGWATFLVQSLGRFEGQ VRQKVRIVSREAEAAEAEEPWGEEA REGRRRGPRRESKPEEPPPPKKPAL DKGLGTGQGAVSGPPRKPPGTVAGT ARGPEGGSTAQVPAPAASPPPEGPV LTFQSEKMKGMKELLVATKINSSAI KLQLTAQSQVQMKKQKVSTPSDYTL SFLKRQRKGLTRTRPLEQKLISEED LAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
