Recombinant Full Length Human UGT1A1, Flag-tagged
Cat.No. : | UGT1A1-1927HFL |
Product Overview : | Recombinant Full Length Human UGT1A1, fused with C-terminal Flag tag, was expressed in mamanlian cells. |
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Source : | Mamanlian cells |
Species : | Human |
Tag : | Flag |
Molecular Mass : | 59.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Storage : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Shipping : | The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below. |
Gene Name : | UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 [ Homo sapiens (human) ] |
Official Symbol : | UGT1A1 |
Synonyms : | UGT1A1; UDP glucuronosyltransferase 1 family, polypeptide A1; GNT1; UGT1; UDPGT; UGT1A; HUG-BR1; BILIQTL1; UDPGT 1-1; UDP-glucuronosyltransferase 1-1; UDP glycosyltransferase 1 family, polypeptide A1; UDP-glucuronosyltransferase 1-A; UDP-glucuronosyltransferase 1A1; UGT-1A; UGT1*1; UGT1-01; UGT1.1; bilirubin UDP-glucuronosyltransferase 1-1; bilirubin UDP-glucuronosyltransferase isozyme 1; bilirubin-specific UDPGT isozyme 1; NP_000454.1; EC 2.4.1.17 |
Gene ID : | 54658 |
mRNA Refseq : | NM_000463 |
Protein Refseq : | NP_000454 |
MIM : | 191740 |
UniProt ID : | P22309 |
Products Types
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UGT1A1-56H | Recombinant Human UGT1A1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
UGT1A1-513HCL | Recombinant Human UGT1A1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (2)
Write a reviewThe product was kept in perfect condition and delivered on time so that I got the perfect product in the shortest time possible.
Customer service contacted me in a timely manner and helped me solve a lot of problems that arose in my experiments.
Q&As (5)
Ask a questionUGT1A1 converts lipophilic small molecules, such as drugs, into water-soluble and excretable metabolites.
Bilirubin is a binding substrate for UGT1A1 and UGT1A1 is involved in bilirubin metabolism.
UGT1A1 is involved in lung cancer, colorectal cancer and hyperbilirubinemia, among other diseases.
UGT1A1 is mainly expressed in the liver.
Mutations in the UGT1A1 gene prevent the glucuronidation of free bilirubin and reduces bilirubin metabolism and increases serum free bilirubin levels.
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