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Recombinant Full Length Mouse Interleukin-4 Receptor Subunit Alpha(Il4R) Protein, His-Tagged

Cat.No. : RFL13636MF
Product Overview : Recombinant Full Length Mouse Interleukin-4 receptor subunit alpha(Il4r) Protein (P16382) (26-810aa), fused to N-terminal His tag, was expressed in E. coli.
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Source : E.coli expression system
Species : Mus musculus (Mouse)
Tag : His
Form : Lyophilized powder
Protein length : Full Length of Mature Protein (26-810)
AA Sequence : IKVLGEPTCFSDYIRTSTCEWFLDS AVDCSSQLCLHYRLMFFEFSENLTC IPRNSASTVCVCHMEMNRPVQSDRY QMELWAEHRQLWQGSFSPSGNVKPL APDNLTLHTNVSDEWLLTWNNLYPS NNLLYKDLISMVNISREDNPAEFIV YNVTYKEPRLSFPINILMSGVYYTA RVRVRSQILTGTWSEWSPSITWYNH FQLPLIQRLPLGVTISCLCIPLFCL FCYFSITKIKKIWWDQIPTPARSPL VAIIIQDAQVPLWDKQTRSQESTKY PHWKTCLDKLLPCLLKHRVKKKTDF PKAAPTKSLQSPGKAGWCPMEVSRT VLWPENVSVSVVRCMELFEAPVQNV EEEEDEIVKEDLSMSPENSGGCGFQ ESQADIMARLTENLFSDLLEAENGG LGQSALAESCSPLPSGSGQASVSWA CLPMGPSEEATCQVTEQPSHPGPLS GSPAQSAPTLACTQVPLVLADNPAY RSFSDCCSPAPNPGELAPEQQQADH LEEEEPPSPADPHSSGPPMQPVESW EQILHMSVLQHGAAAGSTPAPAGGY QEFVQAVKQGAAQDPGVPGVRPSGD PGYKAFSSLLSSNGIRGDTAAAGTD DGHGGYKPFQNPVPNQSPSSVPLFT FGLDTELSPSPLNSDPPKSPPECLG LELGLKGGDWVKAPPPADQVPKPFG DDLGFGIVYSSLTCHLCGHLKQHHS QEEGGQSPIVASPGCGCCYDDRSPS LGSLSGALESCPEGIPPEANLMSAP KTPSNLSGEGKGPGHSPVPSQTTEV PVGALGIAVS
Purity : Greater than 90% as determined by SDS-PAGE.
Applications : SDS-PAGE
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Storage : Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Storage Buffer : Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution : We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Gene Name : Il4r
Synonyms : Il4r; Il4ra; Interleukin-4 receptor subunit alpha; IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; CD antigen CD124
UniProt ID : P16382
Gene Name : Il4r
Synonyms : Il4r; Il4ra; Interleukin-4 receptor subunit alpha; IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; CD antigen CD124
UniProt ID : P16382

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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How about function of IL4R? 10/15/2022

IL4R is a synthetic protein that mimics the IL-4 signaling pathway in nature and binds to the IL-4 receptor in cells, which can be used to study the IL-4 signaling pathway and related diseases.

What is the production technology of IL4R? 02/23/2022

Common IL4R production technologies include prokaryotic expression systems and mammalian cell expression systems.

Which application of IL4R in tumor therapy? 01/26/2022

This protein is used in tumor immunotherapy, which can promote anti-tumor immune response and enhance the anti-tumor effect of cytotoxic T lymphocytes.

In what fields does IL4R have applications? 07/09/2021

It is mainly used in immunology, drug research and other fields. It is also widely used in vaccines, biotechnology, cancer treatment and so on.

Are there have application of IL4R in the treatment of asthma? 03/23/2021

IL4R is used to treat severe pheochromocytome-induced aerodoritis and was approved by the FDA as the first drug to treat this disease.

Can IL4R be administered orally? 05/08/2020

IL4R cannot generally be administered orally, and needs to be administered by injection or intravenous drip.

Customer Reviews (3)

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Reviews
06/30/2022

    Easy to attach to the surface of cells or materials.

    09/29/2021

      It has growth factor activity to promote cell growth and proliferation.

      02/27/2019

        In animals or humans caused by the prone production of antibodies.

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