Recombinant Human ANXA13, His-tagged

Currently, there are no known mutations in the ANXA13 gene that have been directly linked to any specific diseases. However, genetic variations in the ANXA13 gene may exist and could potentially contribute to disease susceptibility or affect ANXA13 function. Further studies are needed to explore the genetic variability of ANXA13 and its potential implications in various diseases.

ANXA13, like other annexin proteins, can be found in various cellular compartments or organelles. Annexin proteins have been detected on the plasma membrane, as well as in the cytoplasm, nucleus, mitochondria, endoplasmic reticulum, and lysosomes. The precise subcellular localization of ANXA13 may depend on the specific cell type and experimental conditions.

Mutations in the ANXA13 gene have been associated with certain diseases, such as amyloidosis. Amyloidosis is a disorder characterized by the abnormal accumulation of proteins in various tissues and organs, leading to organ dysfunction. However, research into the specific role of ANXA13 mutations in the development of amyloidosis is still ongoing.

Mutations in the ANXA13 gene have been associated with certain diseases, such as amyloidosis. Amyloidosis is a disorder characterized by the abnormal accumulation of proteins in various tissues and organs, leading to organ dysfunction. However, research into the specific role of ANXA13 mutations in the development of amyloidosis is still ongoing.

ANXA13 has been implicated in certain cancers. For example, studies have suggested that ANXA13 may promote gastric cancer progression by influencing tumor cell growth and metastasis. However, the exact mechanisms and extent of ANXA13 involvement in cancer development and progression are not fully understood and require further investigation.

While the specific physiological processes involving ANXA13 are not well defined, annexins, in general, have been implicated in various cellular functions. Annexin proteins are known to be involved in membrane repair, membrane trafficking, regulation of ion channels, cell signaling, and apoptosis. It is possible that ANXA13 may have similar roles, but further research is needed to determine its specific functions.

ANXA13 is known to be expressed in various tissues, including the brain, kidney, liver, lung, and pancreas, among others. Its expression pattern may vary depending on the cell type and developmental stage.