Recombinant Human ARRB1 Protein, His-tagged

Species :	Human
Source :	E.coli
Tag :	His
Description :	Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011] GeneCards Summary for ARRB1 Gene
Molecular Mass :	48.1 kDa
Endotoxin :	< 0.1 EU per µg protein as determined by LAL test.
Purity :	> 95% as determined by SDS-PAGE and Coomassie blue staining
Stability :	Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Concentration :	Resuspend the protein to the desired concentration in proper buffer.
Storage Buffer :	Lyophilized from a 0.2 µM filtered solution of 20mM Phosphate buffer, 150mM NaCl, pH 7.2.

Gene Name	ARRB1 arrestin, beta 1 [ Homo sapiens ]
Official Symbol	ARRB1
Synonyms	ARRB1; arrestin, beta 1; ARR1; beta-arrestin-1; arrestin 2; ARB1;
Gene ID	408
mRNA Refseq	NM_004041
Protein Refseq	NP_004032
MIM	107940
UniProt ID	P49407