Recombinant Human ATP, His-tagged
| Cat.No. : | ATP6V0A2-10034H |
| Product Overview : | Recombinant Human ATPHis-tag, was expressed in E.coli and purified by Ni-sepharose. |
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| Description : | The protein encoded by this gene is a subunit of the vacuolar ATPase (v-ATPase), an heteromultimeric enzyme that is present in intracellular vesicles and in the plasma membrane of specialized cells, and which is essential for the acidification of diverse cellular components. V-ATPase is comprised of a membrane peripheral V(1) domain for ATP hydrolysis, and an integral membrane V(0) domain for proton translocation. The subunit encoded by this gene is a component of the V(0) domain. Mutations in this gene are a cause of both cutis laxa type II and wrinkly skin syndrome. |
| Source : | E.coli |
| Species : | Human |
| Tag : | His |
| Protein length : | 3-372a.a. |
| Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
| Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
| Gene Name : | ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 [ Homo sapiens ] |
| Official Symbol : | ATP6V0A2 |
| Synonyms : | a2; A2V ATPase; ARCL; ATP6a2; ATP6N1D; ATP6V0A2; ATPase, H+ transporting, lysosomal V0 subunit a isoform 2; ATPase, H+ transporting, lysosomal V0 subunit a2; Infantile malignant osteopetrosis; J6B7; Lysosomal H(+) transporting ATPase V0 subunit a2; Lysosomal H(+)-transporting ATPase V0 subunit a2; Stv1; TJ6; TJ6M; TJ6s; V ATPase 116 kDa isoform a2; V type proton ATPase 116 kDa subunit a; V type proton ATPase 116 kDa subunit a isoform 2; V-ATPase 116 kDa isoform a2; V-type proton ATPase 116 kDa subunit a isoform 2; Vacuolar proton translocating ATPase 116 kDa subunit a; Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2; Vph1; VPP2_HUMAN; WSS; ATP6V0A2 |
| Gene ID : | 23545 |
| mRNA Refseq : | NM_012463.3 |
| Protein Refseq : | NP_036595.2 |
| MIM : | 611716 |
| UniProt ID : | Q9Y487 |
| Chromosome Location : | 12q24.31 |
| Pathway : | Collecting duct acid secretion, organism-specific biosystem; Collecting duct acid secretion, conserved biosystem; Disease, organism-specific biosystem; Epithelial cell signaling in Helicobacter pylori infection, organism-specific biosystem; Epithelial cell signaling in Helicobacter pylori infection, conserved biosystem; Insulin receptor recycling, organism-specific biosystem; Iron uptake and transport, organism-specific biosystem |
| Function : | hydrogen ion transmembrane transporter activity; protein binding |
Products Types
| ◆ Recombinant Protein | ||
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| ATP6V0A2-2150M | Recombinant Mouse ATP6V0A2 Protein | +Inquiry |
| ATP6V0A2-995H | Recombinant Human ATP6V0A2 protein, GST-tagged | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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