Recombinant Human ATP6V0A2 protein, GST-tagged

• Cat.No.: ATP6V0A2-995H
• Product Overview: Human ATP6V0A2 full-length ORF ( AAH22300, 1 a.a. - 372 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a subunit of the vacuolar ATPase (v-ATPase), an heteromultimeric enzyme that is present in intracellular vesicles and in the plasma membrane of specialized cells, and which is essential for the acidification of diverse cellular components. V-ATPase is comprised of a membrane peripheral V(1) domain for ATP hydrolysis, and an integral membrane V(0) domain for proton translocation. The subunit encoded by this gene is a component of the V(0) domain. Mutations in this gene are a cause of both cutis laxa type II and wrinkly skin syndrome. [provided by RefSeq, Jul 2009]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 66.66 kDa
• AA Sequence: MGSLFRSETMCLAQLFLQSGTAYEC LSALGEKGLVQFRDLNQNVSSFQRK FVGEVKRCEELERILVYLVQEINRA DIPLPEGEASPPAPPLKQVLEMQEQ LQKLEVELREVTKNKEKLRKNLLEL IEYTHMLRVTKTFVKRNVEFEPTYE EFPSLESDSLLDYSCMQRLGAKLGF VSGLINQGKVEAFEKMLWRVCKGYT IVSYAELDESLEDPETGEVIKWYVF LISFWGEQIGHKVKKICDCYHCHVY PYPNTAEERREIQEGLNTRIQDLYT VLHKTEDYLRQVLCKAAESVYSRVI QVKKMKAIYHMLNMCSFDVTNKCLI AEVWCPEADLQDLRRALEEGSVRLP SSPLPGTEERLMELINSEKKRK
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 [ Homo sapiens ]
• Official Symbol: ATP6V0A2
• Synonyms: a2; A2V ATPase; ARCL; ATP6a2; ATP6N1D; ATP6V0A2; ATPase, H+ transporting, lysosomal V0 subunit a isoform 2; ATPase, H+ transporting, lysosomal V0 subunit a2; Infantile malignant osteopetrosis; J6B7; Lysosomal H(+) transporting ATPase V0 subunit a2; Lysosomal H(+)-transporting ATPase V0 subunit a2; Stv1; TJ6; TJ6M; TJ6s; V ATPase 116 kDa isoform a2; V type proton ATPase 116 kDa subunit a; V type proton ATPase 116 kDa subunit a isoform 2; V-ATPase 116 kDa isoform a2; V-type proton ATPase 116 kDa subunit a isoform 2; Vacuolar proton translocating ATPase 116 kDa subunit a; Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2; Vph1; VPP2_HUMAN; WSS; ATP6V0A2
• Gene ID: 23545
• mRNA Refseq: NM_012463.3
• Protein Refseq: NP_036595.2
• MIM: 611716
• UniProt ID: Q9Y487