| Description : |
Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70 |
| Source : |
E. coli |
| Species : |
Human |
| Tag : |
His |
| Form : |
Buffered aqueous solution |
| Molecular Mass : |
63.8 kDa |
| Protein length : |
595 |
| AA Sequence : |
MGSSHHHHHHSSGLVPRGSHMSAAT HSPMMQVASGNGDRDPLPPGWEIKI DPQTGWPFFVDHNSRTTTWNDPRVP SEGPKETPSSANGPSREGSRLPPAR EGHPVYPQLRPGYIPIPVLHEGAEN RQVHPFHVYPQPGMQRFRTEAAAAA PQRSQSPLRGMPETTQPDKQCGQVA AAAAAQPPASHGPERSQSPAASDCS SSSSSASLPSSGRSSLGSHQLPRGY ISIPVIHEQNVTRPAAQPSFHQAQK THYPAQQGEYQTHQPVYHKIQGDDW EPRPLRAASPFRSSVQGASSREGSP ARSSTPLHSPSPIRVHTVVDRPQQP MTHRETAPVSQPENKPESKPGPVGP ELPPGHIPIQVIRKEVDSKPVSQKP PPPSEKVEVKVPPAPVPCPPPSPGP SAVPSSPKSVATEERAAPSTAPAEA TPPKPGEAEAPPKHPGVLKVEAILE KVQGLEQAVDNFEGKKTDKKYLMIE EYLTKELLALDSVDPEGRADVRQAR RDGVRKVQTILEKLEQKAIDVPGQV QVYELQPSNLEADQPLQAIMEMGAV AADKGKKNAGNAEDPHTETQQPEAT AAATSNPSSMTDTPGNPAAP |
| Purity : |
＞90% by SDS-PAGE |
| Applications : |
ELISA |
| Storage : |
Store it under sterile conditions at -20 to -80 ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Concentration : |
1.33 mg/ml |
| Storage Buffer : |
Solution in 20mM Tris-HCl (pH8.0), 1mM EDTA, 0.1 mM PMSF, 10% Glycerol. |
