Recombinant Human BIRC3 protein, GST/StrepII-tagged

Cat.No. : BIRC3-69H
Product Overview : Recombinant Human BIRC3 protein, fused with N-terminal GST tag and C-terminal StrepII tag, was expressed in E.coli.
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Source : E.coli
Species : Human
Tag : GST&StrepII
Form : 50 mM Tris HCl, pH 7.5, 500 mM NaCl, 1 mM TCEP, 10% glycerol
Molecular Mass : 40.2 kDa
Protein length : 244-349
Purity : >90% by SDS-PAGE
Storage : Store at -80°C. Thaw quickly and store on ice before use. Avoid repeated freezing and thawing cycles.
Gene Name : BIRC3 baculoviral IAP repeat containing 3 [ Homo sapiens ]
Official Symbol : BIRC3
Synonyms : BIRC3; baculoviral IAP repeat containing 3; API2, baculoviral IAP repeat containing 3; baculoviral IAP repeat-containing protein 3; apoptosis inhibitor 2; c IAP2; cIAP2; hiap 1; inhibitor of apoptosis protein 1; MALT2; mammalian IAP homolog C; MIHC; RNF49; TNFR2 TRAF signaling complex protein; IAP-1; IAP homolog C; RING finger protein 49; baculoviral IAP repeat-containing 3; TNFR2-TRAF signaling complex protein; TNFR2-TRAF-signaling complex protein 1; AIP1; API2; CIAP2; HAIP1; HIAP1; c-IAP2;
Gene ID : 330
mRNA Refseq : NM_001165
Protein Refseq : NP_001156
MIM : 601721
UniProt ID : Q13489
Chromosome Location : 11q22
Pathway : Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; C-MYB transcription factor network, organism-specific biosystem; CD40/CD40L signaling, organism-specific biosystem; Caspase cascade in apoptosi
Function : metal ion binding; protein binding; ubiquitin-protein ligase activity; zinc ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.


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        Q&As (7)

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        What is the primary role of BIRC3 in apoptosis regulation? 10/29/2022

        BIRC3 (cIAP2) inhibits apoptosis, regulating cell death.

        How does BIRC3 interact with other proteins in apoptosis pathways? 08/29/2022

        BIRC3 interacts with proteins in apoptosis pathways, influencing cell survival.

        What role does BIRC3 play in immune responses? 07/12/2022

        BIRC3 plays a role in immune response, especially in inflammation.

        How do genetic variations in BIRC3 affect disease susceptibility? 10/24/2020

        Genetic changes in BIRC3 affect susceptibility to cancers and immune disorders.

        How does BIRC3 contribute to cell survival? 10/12/2019

        It promotes cell survival by blocking apoptosis signals.

        What is the impact of altered BIRC3 activity on inflammatory conditions? 12/30/2017

        Altered BIRC3 activity impacts inflammatory disease progression.

        What potential therapeutic applications arise from targeting BIRC3 in inflammatory and cancerous diseases? 07/07/2017

        Targeting BIRC3 could treat diseases with abnormal apoptosis, like cancer and inflammation.

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