Recombinant Full Length Human BIRC3 Protein

• Cat.No.: BIRC3-36HF
• Product Overview: Recombinant full length Human cIAP2 with a proprietary tag; predicted MWt 95.4kDa inclusive of tag.

Specification

• Description: This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.
• Source: In Vitro Cell Free System
• Species: Human
• Form: Liquid
• Molecular Mass: 95.400kDa inclusive of tags
• Protein Length: 604 amino acids
• AA Sequence: MNIVENSIFL SNLMKSANTF ELKYDLSCEL YRMSTYSTFP AGVPVSERSL ARAGFYYTGV NDKVKCFCCG LMLDNWKRGD SPTEKHKKLY PSCRFVQSLN SVNNLEATSQ PTFPSSVTNS THSLLPGTEN SGYFRGSYSN SPSNPVNSRA NQDFSALMRS SYHCAMNNEN ARLLTFQTWP LTFLSPTDLA KAGFYYIGPG DRVACFACGG KLSNWEPKDN AMSEHLRHFP KCPFIENQLQ DTSRYTVSNL SMQTH
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents: 0.3% Glutathione, 0.79% Tris HCl.

Gene Information

• Gene Name: BIRC3 baculoviral IAP repeat containing 3 [ Homo sapiens ]
• Official Symbol: BIRC3
• Synonyms: BIRC3; baculoviral IAP repeat containing 3; API2, baculoviral IAP repeat containing 3; baculoviral IAP repeat-containing protein 3; apoptosis inhibitor 2; c IAP2; cIAP2; hiap 1; inhibitor of apoptosis protein 1; MALT2; mammalian IAP homolog C; MIHC; RNF4
• Gene ID: 330
• mRNA Refseq: NM_001165
• Protein Refseq: NP_001156
• MIM: 601721
• UniProt ID: Q13489