- Human(12)
Recombinant Human BIRC3
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Cat.No. : | BIRC3-27246TH Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant full length Human cIAP2 with a proprietary tag; predicted MWt 95.4kDa inclusive of tag. |
Description : | This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified. |
Protein length : | 604 amino acids |
Molecular Weight : | 95.400kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Highly expressed in fetal lung, and kidney. In the adult, expression is mainly seen in lymphoid tissues, including spleen, thymus and peripheral blood lymphocytes. |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.31% Glutathione, 0.79% Tris HClNote: Glutathione is reduced |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MNIVENSIFL SNLMKSANTF ELKYDLSCEL YRMSTYSTFP AGVPVSERSL ARAGFYYTGV NDKVKCFCCG LMLDNWKRGD SPTEKHKKLY PSCRFVQSLN SVNNLEATSQ PTFPSSVTNS THSLLPGTEN SGYFRGSYSN SPSNPVNSRA NQDFSALMRS SYHCAMNNEN ARLLTFQTWP LTFLSPTDLA KAGFYYIGPG DRVACFACGG KLSNWEPKDN AMSEHLRHFP KCPFIENQLQ DTSRYTVSNL SMQTH |
Sequence Similarities : | Belongs to the IAP family.Contains 3 BIR repeats.Contains 1 CARD domain.Contains 1 RING-type zinc finger. |
Gene Name : | BIRC3 baculoviral IAP repeat containing 3 [ Homo sapiens ] |
Official Symbol : | BIRC3 |
Synonyms : | BIRC3; baculoviral IAP repeat containing 3; API2, baculoviral IAP repeat containing 3; baculoviral IAP repeat-containing protein 3; apoptosis inhibitor 2; c IAP2; cIAP2; hiap 1; inhibitor of apoptosis protein 1; MALT2; mammalian IAP homolog C; MIHC; RNF4 |
Gene ID : | 330 |
mRNA Refseq : | NM_001165 |
Protein Refseq : | NP_001156 |
MIM : | 601721 |
Uniprot ID : | Q13489 |
Chromosome Location : | 11q22 |
Pathway : | Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; C-MYB transcription factor network, organism-specific biosystem; CD40/CD40L signaling, organism-specific biosystem; |
Function : | metal ion binding; protein binding; ubiquitin-protein ligase activity; zinc ion binding; |
◆ Recombinant Protein
BIRC3-319H | Recombinant Human BIRC3 Protein, His-tagged | +Inquiry |
BIRC3-635H | Active Recombinant Human BIRC3 Protein, GST-tagged, Active | +Inquiry |
BIRC3-190H | Recombinant Human BIRC3, GST-tagged | +Inquiry |
BIRC3-554H | Recombinant Human BIRC3 | +Inquiry |
BIRC3-70H | Recombinant Human BIRC3 protein, His/StrepII-tagged | +Inquiry |
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◆ Lysates
BIRC3-8451HCL | Recombinant Human BIRC3 293 Cell Lysate | +Inquiry |
BIRC3-8450HCL | Recombinant Human BIRC3 293 Cell Lysate | +Inquiry |
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