Recombinant Human BIRC3
| Cat.No. : | BIRC3-27246TH |
| Product Overview : | Recombinant full length Human cIAP2 with a proprietary tag; predicted MWt 95.4kDa inclusive of tag. |
- Specification
- Gene Information
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| Description : | This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified. |
| Protein length : | 604 amino acids |
| Molecular Weight : | 95.400kDa inclusive of tags |
| Source : | Wheat germ |
| Tissue specificity : | Highly expressed in fetal lung, and kidney. In the adult, expression is mainly seen in lymphoid tissues, including spleen, thymus and peripheral blood lymphocytes. |
| Form : | Liquid |
| Purity : | Proprietary Purification |
| Storage buffer : | pH: 8.00Constituents:0.31% Glutathione, 0.79% Tris HClNote: Glutathione is reduced |
| Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
| Sequences of amino acids : | MNIVENSIFLSNLMKSANTFELKYD LSCELYRMSTYSTFPAGVPVSERSL ARAGFYYTGVNDKVKCFCCGLMLDN WKRGDSPTEKHKKLYPSCRFVQSLN SVNNLEATSQPTFPSSVTNSTHSLL PGTENSGYFRGSYSNSPSNPVNSRA NQDFSALMRSSYHCAMNNENARLLT FQTWPLTFLSPTDLAKAGFYYIGPG DRVACFACGGKLSNWEPKDNAMSEH LRHFPKCPFIENQLQDTSRYTVSNL SMQTH |
| Sequence Similarities : | Belongs to the IAP family.Contains 3 BIR repeats.Contains 1 CARD domain.Contains 1 RING-type zinc finger. |
| Gene Name : | BIRC3 baculoviral IAP repeat containing 3 [ Homo sapiens ] |
| Official Symbol : | BIRC3 |
| Synonyms : | BIRC3; baculoviral IAP repeat containing 3; API2, baculoviral IAP repeat containing 3; baculoviral IAP repeat-containing protein 3; apoptosis inhibitor 2; c IAP2; cIAP2; hiap 1; inhibitor of apoptosis protein 1; MALT2; mammalian IAP homolog C; MIHC; RNF4 |
| Gene ID : | 330 |
| mRNA Refseq : | NM_001165 |
| Protein Refseq : | NP_001156 |
| MIM : | 601721 |
| Uniprot ID : | Q13489 |
| Chromosome Location : | 11q22 |
| Pathway : | Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; C-MYB transcription factor network, organism-specific biosystem; CD40/CD40L signaling, organism-specific biosystem; |
| Function : | metal ion binding; protein binding; ubiquitin-protein ligase activity; zinc ion binding; |
Products Types
| ◆ Recombinant Protein | ||
| BIRC3-319H | Recombinant Human BIRC3 Protein, His-tagged | +Inquiry |
| BIRC3-2544H | Recombinant Human BIRC3 Protein, His (Fc)-Avi-tagged | +Inquiry |
| BIRC3-635H | Active Recombinant Human BIRC3 Protein, GST-tagged, Active | +Inquiry |
| BIRC3-190H | Recombinant Human BIRC3, GST-tagged | +Inquiry |
| BIRC3-2540H | Recombinant Human BIRC3 protein, His-tagged | +Inquiry |
| ◆ Lysates | ||
| BIRC3-8451HCL | Recombinant Human BIRC3 293 Cell Lysate | +Inquiry |
| BIRC3-8450HCL | Recombinant Human BIRC3 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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