Recombinant Human CA2 Protein, GST-Tagged
Cat.No. : | CA2-0238H |
Product Overview : | Human CA2 full-length ORF (NP_000058.1, 1 a.a. - 260 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
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Description : | The protein encoded by this gene is one of several isozymes of carbonic anhydrase, which catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 55.6 kDa |
AA Sequence : | MSHHWGYGKHNGPEHWHKDFPIAKG ERQSPVDIDTHTAKYDPSLKPLSVS YDQATSLRILNNGHAFNVEFDDSQD KAVLKGGPLDGTYRLIQFHFHWGSL DGQGSEHTVDKKKYAAELHLVHWNT KYGDFGKAVQQPDGLAVLGIFLKVG SAKPGLQKVVDVLDSIKTKGKSADF TNFDPRGLLPESLDYWTYPGSLTTP PLLECVTWIVLKEPISVSSEQVLKF RKLNFNGEGEPEELMVDNWRPAQPL KNRQIKASFK |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | CA2 carbonic anhydrase II [ Homo sapiens ] |
Official Symbol : | CA2 |
Synonyms : | CA2; carbonic anhydrase II; carbonic anhydrase 2; CA II; CAII; Car2; CAC; carbonic anhydrase B; carbonic anhydrase C; carbonic dehydratase; carbonate dehydratase II; CA-II; |
Gene ID : | 760 |
mRNA Refseq : | NM_000067 |
Protein Refseq : | NP_000058 |
MIM : | 611492 |
UniProt ID : | P00918 |
Products Types
◆ Recombinant Protein | ||
CA2-201H | Recombinant Human CA2 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
CA2-425R | Recombinant Rhesus Macaque CA2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Car2-765M | Recombinant Mouse Car2 Protein, MYC/DDK-tagged | +Inquiry |
CA2-114H | Recombinant Human CA2 Protein, His-tagged | +Inquiry |
CA2-479H | Recombinant Human CA2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
CA2-31M | Native Mouse Carbonic Anhydrase II (CA2) Protein | +Inquiry |
CA2-35R | Native Rhesus monkey Carbonic Anhydrase II (CA2) Protein | +Inquiry |
CA2-29D | Native Dog Carbonic Anhydrase II (CA2) Protein | +Inquiry |
◆ Lysates | ||
CA2-7915HCL | Recombinant Human CA2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionCA2 deficiency is a rare autosomal recessive disorder with metabolic acidosis and osteopetrosis.
Acetazolamide is a known inhibitor, used clinically for glaucoma and altitude sickness.
Some mutations can lead to CA2 deficiency, affecting acid-base balance and leading to metabolic acidosis.
CA2 is one of the most efficient and fastest enzymes, displaying higher activity than many other isoforms.
CA2 accelerates the reversible conversion of CO2 and water to bicarbonate and protons, aiding in pH regulation.
CA2 plays a crucial role in CO2 transport and acid-base balance in various tissues.
CA2 is ubiquitously expressed but is particularly abundant in red blood cells and certain epithelial tissues.
Customer Reviews (3)
Write a reviewEfficient sample processing, a time-saving boon for researchers.
Professional expertise, elevates our protein research projects.
Invaluable assistance for intricate protein experiments.
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