Description : |
CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia. |
Source : |
Mammalian cells |
Species : |
Human |
Tag : |
C-His |
Form : |
Lyophilized powder/frozen liquid |
Molecular Mass : |
33.09 kDa |
Protein Length : |
Val43-Ile300 |
Endotoxin : |
< 1.0 EU/μg of the protein as determined by the LAL method. |
Purity : |
>90% as determined by SDS-PAGE. |
Notes : |
For research use only. |
Storage : |
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
Storage Buffer : |
Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5. |
Reconstitution : |
Reconstitute in sterile water for a stock solution. |
Shipping : |
They are shipped out with dry ice/blue ice unless customers require otherwise. |