cd38
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  • Official Full Name
  • CD38 molecule
  • Background
  • CD38 (cluster of differentiation 38), also known as cyclic ADP ribose hydrolase, is a transmembrane glycoprotein found on the surface of some immune cells including plasma cells, activated or immature T and B cells, monocytes, and natural killer cells. CD38 participates in cell adhesion, signal transduction and calcium signaling. It is expressed at high levels in the plasma cell tumor, prostate cancer, stomach cancer, and neuroblastoma. CD38 is used as one of the plasma cell markers and its ligand is CD31 molecules.
  • Synonyms
  • CD38; CD38 molecule; ADP-ribosyl cyclase 1; CD38H; cADPr hydrolase 1; cyclic ADP-ribose hydrolase 1; CD38 antigen (ADP-ribosyl cyclase / cyclic ADP-ribose hydrolase)
Cat.#:CD38-1185CATag:Fc
Source (Host):HEK293Species:Cynomolgus
Product nameRecombinant Cynomolgus CD38 protein, Fc-tagged, APC labeled
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Cat.#:CD38-1185CPTag:Fc
Source (Host):HEK293Species:Cynomolgus
Product nameRecombinant Cynomolgus CD38 protein, Fc-tagged, R-PE labeled
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Cat.#:CD38-361HTag:LIgG2b Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD38 Protein, LIgG2b Fc-tagged, low endotoxin
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Cat.#:CD38-362HTag:MIgG2a Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD38 Protein, MIgG2a Fc-tagged, low endotoxin
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Cat.#:CD38-443HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD38 Protein (Va43-Ile300), His-tagged, Biotinylated
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Cat.#:CD38-574HATag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD38 protein, Fc-tagged, APC labeled
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Cat.#:CD38-574HPTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD38 protein, Fc-tagged, R-PE labeled
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Cat.#:Cd38-8742RATag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Cd38 protein, Fc-tagged, APC labeled
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Cat.#:Cd38-8742RPTag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Cd38 protein, Fc-tagged, R-PE labeled
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Cat.#:CD38-0797HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CD38 Protein, GST-Tagged
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Cat.#:CD38-1822HTag:His/AVI
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD38 protein, His & Avi-tagged, Biotinylated
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Cat.#:CD38-27749THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human CD38
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Cat.#:CD38-573HTag:Fc
Source (Host):Human cellsSpecies:Human
Product nameRecombinant Human CD38, Fc-tagged, Biotinylated
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Cat.#:CD38-574HTag:Fc
Source (Host):Human cellsSpecies:Human
Product nameRecombinant Human CD38, Fc-tagged
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Cat.#:CD38-59HTag:His
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human CD38 protein, His-tagged
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Cat.#:CD38-653HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD38, His tagged
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Cat.#:CD38-654HTag:His/Flag
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD38 protein, His/Flag-tagged
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Cat.#:CD38-655HTag:Strep II
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD38 protein, StrepII-tagged
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Cat.#:CD38-7614HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CD38 protein, His & T7-tagged
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Cat.#:Cd38-3112MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Cd38, His tagged
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Cat.#:Cd38-536MTag:His
Source (Host):NSO cellsSpecies:Mouse
Product nameRecombinant Mouse Cd38, His-tagged
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Cat.#:Cd38-7615MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Cd38 protein, His & T7-tagged
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Cat.#:CD38-1249RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CD38 Protein
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Cat.#:Cd38-7616RTag:His/T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Cd38 protein, His & T7-tagged
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Cat.#:Cd38-8742RTag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Cd38, Fc tagged
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Cat.#:Cd38-8743RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Cd38, His tagged
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Cat.#:CD38-1185CTag:Fc
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus CD38 Protein, Fc-tagged
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Cat.#:CD38-388CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus CD38 Protein, His-tagged
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Cat.#:CD38-61CTag:His
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRcombinant Cynomolgus CD38, His-tagged
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Cat.#:CD38-737RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CD38 Protein, His-tagged
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Cat.#:CD38-1027RTag:His
Source (Host):HEK293Species:Rabbit
Product nameRecombinant Rabbit CD38 Protein, His-tagged
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Cat.#:CD38-4486CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CD38
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Cat.#:CD38-1557HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD38 cell lysate
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Cat.#:CD38-2639MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CD38 cell lysate
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Cat.#:CD38-1259RCLTag:
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat CD38 cell lysate
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Cat.#:CD38-1398CCLTag:
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus CD38 cell lysate
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Cat.#:CD38-1025RCLTag:
Source (Host):HEK293Species:Rabbit
Product nameRecombinant Rabbit CD38 cell lysate
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Cat.#:CDA087PTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CD-38
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Involved Pathway

CD38 involved in several pathways and played different roles in them. We selected most pathways CD38 participated on our site, such as Nicotinate and nicotinamide metabolism, Metabolic pathways, Calcium signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD38 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Nicotinate and nicotinamide metabolism
NT5C; ENPP1; BST1; NT5E; NT5C2; ENPP3; QPRT; NT5C1A; NT5C1AA; NADKB
Metabolic pathways
SPR; ATP6V0A2; CKMT2B; LDHBB; GLS2; ASS1; ALAD; MAN1A1; IDH3A; IDH3B
Calcium signaling pathway
HTR2CL1; P2RX4B; GNAS; EGFRA; SLC8A1A; CAMK4; PLCE1; PRKCBB; SLC25A5; CALM1A
Hematopoietic cell lineage
DNTT; CD5; GP1BA; CD4; IL1R2; KIT; CD37; CD7; Itgam&Itgb2; THPO
Oxytocin signaling pathway
PLCB1; PPP3R2; NFATC4; PLCB2; CAMK2A; PLA2G4D; CACNB4; NRAS; CACNA2D1; PRKACG
Salivary secretion
PRH2; CALM3; CD38; CALML5; CST3; LYZ; CALM4; RYR3; AMY1A; ATP1B4
Pancreatic secretion
FXYD2; CELA3A; CTRL; KCNQ1; RAP1B; AMY2A; ATP1A2; ATP1B4; RAP1A; CLCA2
Epstein-Barr virus infection
POLR2B; PSMD1; NFKB1; POLR1C; POLR3GL; MAP2K3; SHFM1; ENTPD3; CD44; EP300

Protein Function

CD38 has several biochemical functions, for example, NAD(P)+ nucleosidase activity, NAD+ nucleosidase activity, phosphorus-oxygen lyase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CD38 itself. We selected most functions CD38 had, and list some proteins which have the same functions with CD38. You can find most of the proteins on our site.
Function
Related Protein
Function NAD(P)+ nucleosidase activity
Related Protein BST1; CD38
Function NAD+ nucleosidase activity
Related Protein CD38; ART5; BST1
Function phosphorus-oxygen lyase activity
Related Protein BST1; ADCY1B; ADCY1A; GUCY2E; ADCY2B; GUCY2F; CD38; GC3; NPR1A; GC2
Function transferase activity
Related Protein RPS6KA3B; PDSS1; ALPK2; PDXKB; NADKD1; ZDHHC21; UGT1B4; AGXTB; SETD1B; NIM1

CD38 Related Articles

Schubert, RD; Hu, Y; et al. IFN-beta Treatment Requires B Cells for Efficacy in Neuroautoimmunity. JOURNAL OF IMMUNOLOGY 194:2110-2116(2015).
Franquesa, M; Mensah, FK; et al. Human Adipose Tissue-Derived Mesenchymal Stem Cells Abrogate Plasmablast Formation and Induce Regulatory B Cells Independently of T Helper Cells. STEM CELLS 33:880-891(2015).