Official Full Name | CD38 molecule |
Background | CD38 (cluster of differentiation 38), also known as cyclic ADP ribose hydrolase, is a transmembrane glycoprotein found on the surface of some immune cells including plasma cells, activated or immature T and B cells, monocytes, and natural killer cells. CD38 participates in cell adhesion, signal transduction and calcium signaling. It is expressed at high levels in the plasma cell tumor, prostate cancer, stomach cancer, and neuroblastoma. CD38 is used as one of the plasma cell markers and its ligand is CD31 molecules. |
Synonyms | CD38; CD38 molecule; ADP-ribosyl cyclase 1; CD38H; cADPr hydrolase 1; cyclic ADP-ribose hydrolase 1; CD38 antigen (ADP-ribosyl cyclase / cyclic ADP-ribose hydrolase) |
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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CD38 involved in several pathways and played different roles in them. We selected most pathways CD38 participated on our site, such as Nicotinate and nicotinamide metabolism, Metabolic pathways, Calcium signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD38 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Nicotinate and nicotinamide metabolism | NT5C3L; NT5C2A; NT5C1A; NADKD1; PNP6; NT5M; NUDT12; NT5C1AA; KCNG4; QPRT |
Metabolic pathways | DEGS2; G6PD; DAO.3; DAO.1; CYP2C38; GLULB; PGAM1; PDHB; PLD1; ST3GAL1 |
Calcium signaling pathway | CAMK2G1; PTK2BB; PLCD1; MYLK2; HTR4; ORAI3; PPP3R1B; PHKA2; ORAI1; ORAI1B |
Hematopoietic cell lineage | CD1d1; MME; IL6R; TFRC; IL4; CD34; CD37; IL6; IL3RA; ITGA2 |
Oxytocin signaling pathway | CACNA2D1; PLCB3; ROCK2; RCAN1; MYL6; CAMK2G; NFATC4; CACNG4; PIK3CA; CAMKK2 |
Salivary secretion | RYR3; PRKACA; ATP1B3; Slc4a2; CAP18; PRKG1; GNAS; CD38; ITPR1; ITPR3 |
Pancreatic secretion | PLA2G10; AMY2A; Adcy4; ATP1B1; ATP1A1; CPB2; RAP1A; PNLIPRP1; PNLIPRP2; PLA2G2A |
Epstein-Barr virus infection | TBPL1; GTF2B; PSMC1; HDAC1; POLR2J2; HSPA2; NCOR2; PIK3CB; LYN; POLR3G |
CD38 has several biochemical functions, for example, NAD(P)+ nucleosidase activity, NAD+ nucleosidase activity, phosphorus-oxygen lyase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CD38 itself. We selected most functions CD38 had, and list some proteins which have the same functions with CD38. You can find most of the proteins on our site.
Function | Related Protein |
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NAD(P)+ nucleosidase activity | CD38; BST1 |
NAD+ nucleosidase activity | ART5; CD38; BST1 |
phosphorus-oxygen lyase activity | GUCY2E; ADCY1A; ADCY1B; GUCY2F; GC2; ADCY2B; NPR1A; CD38; GC3; BST1 |
transferase activity | EHMT1A; FUT9D; CAMK1DA; CD38; PTAR1; GXYLT1B; CAMKK1A; UGT5G1; INSRA; BMPR2B |
CD38 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD38 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD38.
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