Recombinant Human CD70 protein, His-tagged
| Cat.No. : | CD70-56H |
| Product Overview : | Recombinant human CD70, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
| Description : | CD70, also known as CD70 antigen, is a transmembrane protein in the TNF receptor superfamily. It functions as a co-stimulatory molecule that supports lymphocyte activation and survival. This protein binds to the transmembrane glycoprotein CD27 ligand/CD70 which is expressed on activated B cells, activated T cells, and dendritic cells. Binding of CD70 to its receptor CD27 induces in priming, effector functions, differentiation and memory formation of T cell activation, and thus is proliferation of co-stimulated T cells, as well as the generation of cytolytic T cells. |
| Source : | Insect cells |
| Species : | Human |
| Tag : | His tag |
| Form : | Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
| Molecular Mass : | 18.2kDa (164aa) |
| AA Sequence : | ADPQRFAQAQ QQLPLESLGW DVAELQLNHT GPQQDPRLYW QGGPALGRSF LHGPELDKGQ LRIHRDGIYM VHIQVTLAIC SSTTASRHHP TTLAVGICSP ASRSISLLRL SFHQGCTIAS QRLTPLARGD TLCTNLTGTL LPSRNTDETF FGVQWVRPHH HHHH |
| Endotoxin : | < 1.0 EU per 1 microgram of protein (determined by LAL method) |
| Purity : | >90% by SDS - PAGE |
| Storage : | Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20Centigrade or -70Centigrade. Avoid repeated freezing and thawing cycles. |
| Concentration : | 0.25mg/ml (determined by Absorbance at 280nm) |
| Gene Name : | CD70 CD70 molecule [ Homo sapiens ] |
| Official Symbol : | CD70 |
| Synonyms : | CD70; CD70 molecule; CD70 antigen; CD27L; CD27-L; CD27LG; TNFSF7 |
| Gene ID : | 970 |
| mRNA Refseq : | NM_001252 |
| Protein Refseq : | NP_001243 |
| MIM : | 602840 |
| UniProt ID : | P32970 |
| Chromosome Location : | 19p13 |
| Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; |
| Function : | cytokine activity; protease binding; protein binding; receptor binding; tumor necrosis factor receptor binding; |
Products Types
| ◆ Lysates | ||
| CD70-2710HCL | Recombinant Human CD70 cell lysate | +Inquiry |
| CD70-1303RCL | Recombinant Rat CD70 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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