CD70

  • Official Full Name

    Cd70 CD70 antigen

  • Synonyms

    CD70; CD70 antigen; CD27-L; CD27 ligand; Ki-24 antigen; tumor necrosis factor ligand superfamily member 7; tumor necrosis factor (ligand) superfamily, member 7; Cd27l; CD27LG; Tnfsf7;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • GMP Proteins
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rhesus monkey
  • Rhesus Monkey
  • CHO
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Human Cell
  • Human cells
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Yeast
  • C
  • His
  • DYKDDDDK
  • Fc
  • Flag
  • GST
  • HA
  • GCN4
  • IZ
  • hFc
  • Avi
  • hIgG1
  • hIgG4
  • His (Fc)
  • His|Flag|StrepII
  • His|GST
  • lFc
  • mFc
  • MIgG1 Fc
  • Mouse|IgG2a|Fc
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
  • 6×His
  • RIgG Fc
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CD70-116H Active Recombinant Human CD70, His-tagged CHO His
Human CD70-218H Active Recombinant Human CD70 Protein, HA/GCN4-IZ-tagged HEK293 HA/GCN4-IZ
Human CD70-639P Active Recombinant Human CD70 protein, Fc-tagged, R-PE labeled HEK293 Fc Gln 39-Pro 193
Human CD70-196H Active Recombinant Human CD70 protein, His-tagged HEK293 His Leu50-Pro193
Human CD70-0848H Recombinant Human CD70 Protein Wheat Germ N/A
Human CD70-6722H Recombinant Human CD70 protein, His & GST-tagged E.coli His/GST Gln47~Val191 (Accession # P32970)
Human CD70-0851H Recombinant Human CD70 Protein, GST-Tagged Wheat Germ GST
Human CD70-0849H Recombinant Human CD70 Protein, His-Flag-StrepII-Tagged Human Cell His/Flag/StrepII
Human CD70-639 Active Recombinant Human CD70 protein, hFc-tagged HEK293 hFc Gln39-Pro193
Human CD70-56H Recombinant Human CD70 protein, His-tagged Insect Cell His
Human CD70-891H Recombinant Human CD70 Protein, Fc-tagged HEK293 Fc
Human CD70-2710HCL Recombinant Human CD70 cell lysate Human Cell N/A
Human CD70-892H Active Recombinant Human CD70 protein, hFc&Avi-tagged, Biotinylated HEK293 hFc&Avi Gln39-Pro193
Human CD70-437H Recombinant Human CD70 Protein (Gln39-Pro193), RIgG Fc-tagged HEK293 RIgG Fc Gln39-Pro193
Human CD70-891HA Recombinant Human CD70 protein, Fc-tagged, APC labeled HEK293 Fc
Human CD70-073H Active Recombinant Human CD70, hFc-tagged HEK293 hFc Ser52-Pro193
Human CD70-639A Recombinant Human CD70 protein, Fc-tagged, APC labeled HEK293 Fc
Human CD70-328H Active Recombinant Human CD70 protein, lFc-tagged HEK293 lFc Ser 52 - Pro 193
Human CD70-436H Recombinant Human CD70 Protein (Gln39-Pro193), MIgG1 Fc-tagged HEK293 MIgG1 Fc Gln39-Pro193
Human CD70-545H Recombinant Human CD70 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human CD70-089H Recombinant Human CD70 protein, His-Flag-tagged HEK293 His-Flag It contains Gln50-Pro193 Trimer.
Human CD70-3030HF Recombinant Full Length Human CD70 Protein In Vitro Cell Free System 392 amino acids
Human CD70-328HG Active GMP Recombinant Human CD70 protein HEK293 DNA sequence encoding Human CD27 Ligand(UniProtKB/Swiss-Prot: P32970.2) was expressed with His tag at the C-terminal.
Human CD70-623H Recombinant Human CD70 Protein, Fc-tagged HEK293 Fc 193
Human CD70-151H Recombinant Human CD70 Protein, DYKDDDDK-tagged Human cells DYKDDDDK
Human CD70-206H Recombinant Human CD70 Protein, C-His-tagged E.coli C-His
Human CD70-2517H Recombinant Human CD70 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CD70-2985H Active Recombinant Human CD70 protein, His-Flag-tagged, FITC-Labeled HEK293 His-Flag Ser 52-Pro 193
Human CD70-891HAF555 Recombinant Human CD70 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc
Human CD70-5366H Recombinant Human CD70 Protein (Gln39-Pro193), N-His tagged Mammalian cells N-His Gln39-Pro193
Human CD70-639F Recombinant Human CD70 Protein, Fc-tagged, FITC conjugated HEK293 Fc 413
Human CD70-038H Recombinant Human CD70 Protein, Leu50-Pro193, N-His tagged, Biotinylated HEK293 N-His Leu50-Pro193
Human CD70-891HAF647 Recombinant Human CD70 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc
Human CD70-3100H Recombinant Human CD70 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human CD70-072H Active Recombinant Human CD70 Protein, His-Flag-tagged HEK293 His-Flag Ser52-Pro193
Human CD70-891HP Recombinant Human CD70 protein, Fc-tagged, R-PE labeled HEK293 Fc
Human CD70-891HF Recombinant Human CD70 Protein, Fc-tagged, FITC conjugated HEK293 Fc
Human CD70-435H Recombinant Human CD70(Gln45-Pro193) Protein, C-mFc-tagged HEK293 mFc
Human CD70-545H-B Recombinant Human CD70 Protein Pre-coupled Magnetic Beads HEK293
Human CD70-639AF488 Recombinant Human CD70 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc 413
Human CD70-3055HF Recombinant Full Length Human CD70 Protein, GST-tagged In Vitro Cell Free System GST 193 amino acids
Human CD70-639AF647 Recombinant Human CD70 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc 413
Human CD70-2986H Active Recombinant Human CD70 protein, His-Avi-Flag-tagged, Biotinylated HEK293 His-Avi-Flag Ser 52-Pro 193
Human CD70-5373H Recombinant Human CD70 protein, His-tagged Yeast His 39-193
Human CD70-375HFL Active Recombinant Full Length Human CD70 Protein, C-Flag-tagged Mammalian cells Flag
Human CD70-891HAF488 Recombinant Human CD70 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc
Human CD70-514H Recombinant Human CD70 Protein (Gln39-Pro193), N-hFc and C-6×His-tagged HEK293 N-hFc and C-6×His Gln39-Pro193
Human CD70-639AF555 Recombinant Human CD70 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc 413
Human CD70-515H Recombinant Human CD70 Protein (Gln39-Pro193), N-mFc and C-6×His-tagged HEK293 N-mFc and C-6×His Gln39-Pro193
Human CD70-5365H Recombinant Human CD70 Protein (Gln39-Pro193), N-Fc tagged Mammalian cells N-Fc Gln39-Pro193
Human CD70-324H Active Recombinant Human CD70 Protein (Gln39-Pro193), N-His tagged, Animal-free, Carrier-free E.coli N-His Gln39-Pro193
Mouse CD70-3105M Recombinant Mouse CD70 Protein Mammalian Cell His
Mouse Cd70-6723M Recombinant Mouse Cd70 protein, His-tagged E.coli His Leu64~Trp192 (Accession # O55237)
Mouse Cd70-972M Active Recombinant Mouse Cd70 protein(Gln47-Pro159), mFc-tagged HEK293 N-mFc Gln47-Pro159
Mouse Cd70-972MF Recombinant Mouse Cd70 Protein, Fc-tagged, FITC conjugated HEK293 Fc 385
Mouse Cd70-972MA Recombinant Mouse Cd70 protein, Fc-tagged, APC labeled HEK293 Fc
Mouse Cd70-87M Active Recombinant Mouse Cd70 Protein (Gln47-Pro195), N-His tagged, Animal-free, Carrier-free E.coli N-His Gln47-Pro195
Mouse CD70-329M Recombinant Mouse CD70 protein (active trimer)(HPLC-verified), His-tagged HEK293 His 149
Mouse Cd70-972MAF647 Recombinant Mouse Cd70 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc 385
Mouse CD70-330M Recombinant Mouse CD70 protein, Mouse IgG2a Fc-tagged, low endotoxin HEK293 Mouse/IgG2a/Fc 149
Mouse Cd70-972MAF555 Recombinant Mouse Cd70 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc 385
Mouse CD70-1467M-B Recombinant Mouse CD70 Protein Pre-coupled Magnetic Beads HEK293
Mouse Cd70-972MP Recombinant Mouse Cd70 protein, Fc-tagged, R-PE labeled HEK293 Fc
Mouse Cd70-2065M Recombinant Mouse Cd70 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse CD70-2987M Active Recombinant Mouse CD70 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Gln 47-Pro 195
Mouse CD70-1467M Recombinant Mouse CD70 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CD70-2988M Active Recombinant Mouse CD70 protein, His-tagged HEK293 His Gln 47-Pro 195
Mouse CD70-2989M Active Recombinant Mouse CD70 protein, mFc-tagged HEK293 mFc Gln 47-Pro 195
Mouse Cd70-972MAF488 Recombinant Mouse Cd70 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc 385
Rat Cd70-8730R Active Recombinant Rat Cd70 protein, hFc-tagged HEK293 hFc Gln46-Pro195
Rat Cd70-8731R Active Recombinant Rat Cd70 protein, His-tagged HEK293 His Gln46-Pro195
Rat CD70-1303RCL Recombinant Rat CD70 cell lysate Human Cell N/A
Rat Cd70-8730RF Recombinant Rat Cd70 Protein, Fc-tagged, FITC conjugated HEK293 Fc 410
Rat Cd70-8730RA Recombinant Rat Cd70 protein, Fc-tagged, APC labeled HEK293 Fc
Rat Cd70-8731RAF488 Recombinant Rat Cd70 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His 170
Rat Cd70-8731RAF647 Recombinant Rat Cd70 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His 170
Rat Cd70-8730RAF555 Recombinant Rat Cd70 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc 410
Rat Cd70-8730RAF647 Recombinant Rat Cd70 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc 410
Rat Cd70-8731RF Recombinant Rat Cd70 Protein, His-tagged, FITC conjugated HEK293 His 170
Rat Cd70-8730RAF488 Recombinant Rat Cd70 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc 410
Rat Cd70-8730RP Recombinant Rat Cd70 protein, Fc-tagged, R-PE labeled HEK293 Fc
Rat Cd70-8731RAF555 Recombinant Rat Cd70 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His 170
Rhesus monkey CD70-1804R Recombinant Rhesus Monkey CD70 Protein HEK293 N/A
Rhesus monkey CD70-1805R Recombinant Rhesus Monkey CD70 Protein, hIgG1-tagged HEK293 hIgG1
Rhesus monkey CD70-1806R Recombinant Rhesus Monkey CD70 Protein, hIgG4-tagged HEK293 hIgG4
Rhesus Monkey CD70-01H Recombinant Rhesus Monkey CD70 Protein, his-tagged HEK293 His 157
Cynomolgus CD70-105C Recombinant Cynomolgus CD70 protein, His-tagged HEK293 His Gln39-Pro194
Mus musculus (Mouse) RFL17124MF Recombinant Full Length Mouse Cd70 Antigen(Cd70) Protein, His-Tagged E.coli expression system His Full Length (1-195)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

CD70 involved in several pathways and played different roles in them. We selected most pathways CD70 participated on our site, such as Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD70 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionIFN-a;CXCL10;CSF2RB;IFNPHI3;PRP2;CCR9A;GHRA;TGFB1A;CXCL16

CD70 has several biochemical functions, for example, cytokine activity, protease binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD70 itself. We selected most functions CD70 had, and list some proteins which have the same functions with CD70. You can find most of the proteins on our site.

Function Related Protein
cytokine activityBMP15;CMTM5;SPAW;IL31;LFT1;Fasl;LFT2;CMTM1;WNT2
protease bindingCstb;PEO1;INS1;INS2;FLOT1;SERPINB4;SERPINC1;TIMP2;TRP53
protein bindingCAMLG;SRSF7;SH3GL3;Shh;SDHB;DIS3;RIPK2;CD82;USP37
receptor bindingAPOF;F7;HCK;RASA1;WNT7A;GNB2L1;P2RX4;PGR;DRD1A
tumor necrosis factor receptor bindingFasl;ERAP1;TNFSF12;TNFSF4;TNFSF11;TNFSF9;TRAF4;TNFB;TRAF6

CD70 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD70 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD70.

Gene Family

TNF Cytokines

Research Area

Related articles

Convers, KD; Kariuki, BM; et al. Decreased CD5(-)CD19(+)CD27(+)CD43(+)CD70(-) B-Cell Subpopulation in Children with Specific Antibody Deficiency. PEDIATRIC ALLERGY IMMUNOLOGY AND PULMONOLOGY 28:27-31(2015).
Tannir, NM; Forero-Torres, A; et al. Phase I dose-escalation study of SGN-75 in patients with CD70-positive relapsed/refractory non-Hodgkin lymphoma or metastatic renal cell carcinoma. INVESTIGATIONAL NEW DRUGS 32:1246-1257(2014).
  • Q&As
  • Reviews

Q&As (5)

Ask a question
What are some potential CD70-targeted therapies for cancer? 04/29/2023

Antibodies, antibody-drug conjugates, and chimeric antigen receptor (CAR) T-cell therapies are being developed to target CD70 in cancer.

How can CD70-targeted therapies improve cancer treatment outcomes? 05/03/2022

CD70-targeted therapies can enhance the body's immune response against cancer cells and potentially lead to more effective treatments.

In which hematological malignancies is CD70 expression frequently observed? 04/08/2021

CD70 expression is often observed in Hodgkin's lymphoma and certain types of T-cell lymphomas.

Are there any challenges in developing CD70-targeted therapies for cancer? 03/14/2020

Challenges include potential toxicities and finding the right balance to target CD70 effectively without harming normal immune functions.

Are there clinical trials involving CD70-targeted therapies for cancer treatment? 11/14/2018

Yes, there are ongoing clinical trials exploring CD70-targeted therapies for various cancer types.

Customer Reviews (3)

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Reviews
05/31/2021

    Their collaboration, expertise, and customized solutions contribute to the successful execution of experiments, reliable data generation, and the advancement of scientific knowledge in the field.

    04/23/2019

      the manufacturer's support is crucial for researchers using CD70 protein in trials.

      03/07/2017

        These resources can enhance the efficiency and accuracy of experimental workflows and contribute to successful outcomes.

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