Recombinant Human Chemokine (C-C motif) Ligand 21
| Cat.No. : | CCL21-341H |
| Product Overview : | Recombinant human CCL21is a single, non-glycosylated polypeptide chain containing 111 amino acids.CCL21 is expressed in E. coli, MW 12.2 kDa. |
- Specification
- Gene Information
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| Cat. No. : | CCL21-341H |
| Description : | Chemokine (C-Cmotif) ligand 21 (CCL21) is a small cytokine belonging to the CC chemokinefamily. This chemokine is also known as 6Ckine (because it has six conservedcysteine residues instead of the four cysteines typical to chemokines),exodus-2, and secondary lymphoid-tissue chemokine (SLC). The gene for CCL21is located on human chromosome 9. CCL21 elicits its effects by binding to acell surface chemokine receptor known as CCR7. |
| Source : | Human |
| Host : | E. coli |
| Form : | Lyophilizedfrom a sterile filtered solution in 20 mM PB, pH 7.4 + 150 mM NaCl. |
| Purity : | > 97% asdetermined by HPLC and SDS-PAGE analyses. |
| Sequence : | SDGGAQDCCLKYSQRKIPAK VVRSYRKQEP SLGCSIPAIL FLPRKRSQAE LCADPKELWV QQLMQHLDKT PSPQKPAQGCRKDRGASKTG KKGKGSKGCR KTERSQTPKG P |
| Molecular Weight : | 12.2 kDa |
| Biological Activity : | Calculatedby the ability to chemoattract lymphocytes using a concentration of10.0-100.0ng/ml. |
| Endotoxin Level : | < 0.1ng/µg Exodus 2 |
| Reconstitution : | Centrifugevial prior to opening. Add sterile distilled water or aqueous buffer containing0.1% BSA to a concentration of 0.1-1.0 mg/mL. Please note that the additionof any carrier protein into this product may produce unwanted endotoxin. Thisdepends upon the particular application employed. Further dilutions should bemade in appropriate buffered solutions. |
| Storage : | Stableat 2-8°C, but best kept desiccated -20°C. Upon reconstitution, stable for upto 1 week at 2-8°C. For longer term, store in working aliquots below -20°C. Avoidrepeated freeze/thaw cycles. |
| OfficialSymbol : | CCL21 |
| Gene Name : | CCL21chemokine (C-C motif) ligand 21 [ Homo sapiens ] |
| Synonyms : | CCL21; chemokine (C-C motif) ligand 21; ECL; SLC; CKb9; TCA4;6Ckine; SCYA21; MGC34555; C-C motif chemokine 21; exodus-2;OTTHUMP00000021303; OTTHUMP00000021304; beta chemokine exodus-2;beta-chemokine exodus-2; small-inducible cytokine A21; secondary lymphoidtissue chemokine; secondary lymphoid-tissue chemokine; EfficientChemoattractant for Lymphocytes; small inducible cytokine subfamily A(Cys-Cys), member 21 |
| Gene ID : | 6366 |
| mRNA Refseq : | NM_002989 |
| Protein Refseq : | NP_002980 |
| MIM : | 602737 |
| UniProt ID : | O00585 |
| Chromosome Location : | 9p13 |
| Pathway : | Chemokinereceptors bind chemokines; Chemokine signaling pathway; Class A/1(Rhodopsin-like receptors); Cytokine-cytokine receptor interaction; G alpha(i) signalling events; GPCR downstream signaling; GPCR ligand binding;Peptide ligand-binding receptors; Signaling by GPCR |
| Function : | CCR7chemokine receptor binding; chemokine activity |
Products Types
| ◆ Recombinant Protein | ||
| CCL21-0625H | Active Recombinant Human CCL21 Protein | +Inquiry |
| CCL21-2148H | Recombinant Human CCL21 Protein, His-tagged | +Inquiry |
| CCL21-122C | Active Recombinant Human CCL21 Protein (111 aa) | +Inquiry |
| CCL21-4372H | Recombinant Human CCL21 Protein, His (Fc)-Avi-tagged | +Inquiry |
| CCL21-19H | Active Recombinant Human CCL21 Protein | +Inquiry |
| ◆ Lysates | ||
| CCL21-552HCL | Recombinant Human CCL21 cell lysate | +Inquiry |
| CCL21-424CCL | Recombinant Cynomolgus CCL21 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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