CCL21 involved in several pathways and played different roles in them. We selected most pathways CCL21 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, NF-kappa B signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCL21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name |
Pathway Related Protein |
| Cytokine-cytokine receptor interaction |
IL21R.1; TNFRSF11B; VEGFA; HGF; IFNA3; IL7; BMP7B; CXCR7; EPO; CCL4L1 |
| Chemokine signaling pathway |
RAC2; PRKCB; CCL15; KRAS; CXCL2; CX3CL1; CCL16; STAT2; CCL3; ARRB1 |
| NF-kappa B signaling pathway |
IRAK1; PLCG1; TLR4; TNFSF13B; LTBR; CD40LG; PLCG2; CCL13; RELB; TRADD |
CCL21 has several biochemical functions, for example, CCR chemokine receptor binding, CCR7 chemokine receptor binding, chemokine activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CCL21 itself. We selected most functions CCL21 had, and list some proteins which have the same functions with CCL21. You can find most of the proteins on our site.
| Function |
Related Protein |
| CCR chemokine receptor binding |
CCL15; CCL34B.4; CCL22; CCL3L1; CCL19A.1; CCL19A.2; CCL1; CCL38A.5; CXCL32B.1; CCL14 |
| CCR7 chemokine receptor binding |
CCL21; CCL19 |
| chemokine activity |
CCL14; CCL34B.9; CXCL5; CXCL11; Ccl9; CCL21B; PF4; CCL13; Cxcl15; CX3CL1 |
| chemokine receptor binding |
S100A14; CCL21B; CCL25; CCL5; CCL21; Ccl21a; CXCL12; CCL19; CCRL2; Ccl21c |
CCL21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCL21 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCL21.
LRRK1; LRRK2; a41_vaccw; CCR7; GOT2; q81ue9_bacan; UBQLN4
Carubbi, F; Alunno, A; et al. Is minor salivary gland biopsy more than a diagnostic tool in primary Sjogren's syndrome? Association between clinical, histopathological, and molecular features: A retrospective study. SEMINARS IN ARTHRITIS AND RHEUMATISM 44:314-324(2014).
Chadzinska, M; Golbach, L; et al. Characterization and expression analysis of an interferon-gamma 2 induced chemokine receptor CXCR3 in common carp (Cyprinus carpio L.). DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 47:68-76(2014).
