Recombinant Human CNTF Protein
| Cat.No. : | CNTF-148H |
| Product Overview : | Recombinant Human Ciliary Neurotrophic Factor is produced by our E.coli expression system and the target gene encoding Ala2-Met200 is expressed. |
- Specification
- Gene Information
- Related Products
| Description : | Ciliary Neurotrophic Factor (CNTF) is a potent survival factor for neurons and oligodendrocytes. CNTF has also been shown to prevent the degeneration of motor axons after axotomy. CNTF is highly conserved across species and exhibits cross-species activities. Human and rat CNTF share approximately 83% homology in their protein sequence. CNTF is structurally related to IL6, IL11, LIF and OSM. All of these four helix bundle cytokines share gp130 as a signal transducing subunit in their receptor complexes. CNTF, like FGF acidic, FGF basic, and PD-ECGF (platelet-derived endothelial cell growth factor), does not possess a signal sequence that would allow secretion of the factor by classical secretion pathways. The mechanism underlying the release of CNTF is unknown. |
| Source : | E. coli |
| Species : | Human |
| Form : | Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, 1mM Cysteine, pH 7.4. |
| Protein Length : | Ala2-Met200 |
| AA Sequence : | AFTEHSPLTPHRRDLCSRSIWLARK IRSDLTALTESYVKHQGLNKNINLD SADGMPVASTDQWSELT EAERLQENLQAYRTFHV LLARLLEDQQVHFTPTEGDFHQAIH TLLLQVAAFAYQIEELMILLEYKIP RNEADGMPINVGDGGLFEK KLWGLKVLQELSQWT VRSIHDLRFISSHQTGIPARGSHYI ANNKKM |
| Endotoxin : | Less than 0.1 ng/ug (1 EU/ug). |
| Purity : | >95% |
| Storage : | Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days. Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months. |
| Quality Statement : | Purity Greater than 95% as determined by reducing SDS-PAGE. |
| Shipping : | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
| Gene Name : | CNTF ciliary neurotrophic factor [ Homo sapiens (human) ] |
| Official Symbol : | CNTF |
| Synonyms : | Ciliary Neurotrophic Factor; HCNTF |
| Gene ID : | 1270 |
| mRNA Refseq : | NM_000614.4 |
| Protein Refseq : | NP_000605.1 |
| MIM : | 118945 |
| UniProt ID : | P26441 |
Products Types
| ◆ Native Protein | ||
| CNTF-26839TH | Native Human CNTF | +Inquiry |
| ◆ Lysates | ||
| CNTF-376HCL | Recombinant Human CNTF cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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