Recombinant Human CSF2 Protein

• Cat.No.: CSF2-632H
• Product Overview: Human GM-CSF is expressed from mammalian with no tag. It contains Ala18-Glu144.

Specification

• Description: Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony-stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, natural killer cells, endothelial cells and fibroblasts that functions as a cytokine. The pharmaceutical analogs of naturally occurring GM-CSF are called sargramostim and molgramostim.
• Source: HEK293
• Species: Human
• Tag: N/A
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Protein length: Ala18-Glu144
• Endotoxin: Less than 0.5 EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE. > 95% as determined by HPLC.
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: CSF2 colony stimulating factor 2 [ Homo sapiens (human) ]
• Official Symbol: CSF2
• Synonyms: CSF; GMCSF
• Gene ID: 1437
• mRNA Refseq: NM_000758.4
• Protein Refseq: NP_000749.2
• MIM: 138960
• UniProt ID: P04141

Reviews

01/15/2022

The product's adherence to regulatory standards aligned with our lab's commitment to responsible and transparent research.

07/27/2021

The manufacturer's commitment to meeting regulatory requirements demonstrated its dedication to ethical research practices.

05/19/2019

Compliance with industry standards minimized potential roadblocks in securing approvals for our experiments.

Q&As

How conserved is the sequence of CSF2 among different species?

The sequence of CSF2 is moderately conserved across different species.

What is the typical length of CSF2?

The length of CSF2 protein varies but is typically around 144 amino acids.

What is the main biological function of CSF2?

The primary function of CSF2 is to regulate the production and differentiation of white blood cells.

In what tissues or cells is CSF2 commonly expressed?

CSF2 is often expressed in immune cells, specifically in macrophages, T cells, and endothelial cells.

What does CSF2 stand for?

CSF2 stands for Colony Stimulating Factor 2.

Is CSF2 associated with any specific diseases or conditions?

CSF2 dysregulation has been linked to autoimmune diseases and inflammatory disorders.

Which cellular functions are associated with CSF2?

CSF2 is involved in the stimulation of stem cells to produce granulocytes and monocytes.