Recombinant Human CXCL11, StrepII-tagged CXCL11-297H

Recombinant Human CXCL11, StrepII-tagged

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Cat.No. : CXCL11-297H Optional Service: Optional requirements on this protein
Product Overview : Purified, full-length human recombinant CXCL11 protein (amino acids 22-94, 73 a.a.) with StrepII tag, produced in human cells. Predicted molecular weight: 8.3 kDa. (Accession NP_005400; UniProt O14625)
Description : CXCL11 is a member of the intercrine alpha (chemokine CxC) family. It is chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. This protein induces calcium release in activated T-cells and binds to CXCR3. It may play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.
Source : Human Cells
Species : Human
Tag : StrepII
Form : Lyophilized from sterile 0.2μm filtered solution in 0.3X PBS with 10% Trehalose (carrier-free)
Protein length : 22-94, 73 a.a.
AA Sequence : FPMFKRGRCL CIGPGVKAVK VADIEKASIM YPSNNCDKIE VIITLKENKG QRCLNPKSKQ ARLIIKKVER KNF
Endotoxin : <0.1 eu per μg protein by lal
Purity : ~80% by SDS-PAGE
Storage : 12 months at -20°C as supplied; 1 month at 4°C after reconstitution. Avoid freeze/thaw cycles.
Reconstitution : Centrifuge the vial prior to opening. Reconstitute in PBS to a concentration of 0.1 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for up to 1 month.
Gene Name : CXCL11 chemokine (C-X-C motif) ligand 11 [ Homo sapiens ]
Official Symbol : CXCL11
Synonyms : CXCL11; chemokine (C-X-C motif) ligand 11; SCYB9B, SCYB11, small inducible cytokine subfamily B (Cys X Cys), member 11; C-X-C motif chemokine 11; b R1; H174; I TAC; IP 9; beta-R1; small inducible cytokine B11; small-inducible cytokine B11; interferon gamma-inducible protein 9; interferon-inducible T-cell alpha chemoattractant; small inducible cytokine subfamily B (Cys-X-Cys), member 11; small inducible cytokine subfamily B (Cys-X-Cys), member 9B; IP9; IP-9; b-R1; I-TAC; SCYB11; SCYB9B; MGC102770;
Gene ID : 6373
mRNA Refseq : NM_005409
Protein Refseq : NP_005400
MIM : 604852
UniProt ID : O14625
Chromosome Location : 4q21
Pathway : CXCR3-mediated signaling events, organism-specific biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem;
Function : chemokine activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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