CCL11-01H
Optional Service: Optional requirements on this protein
Product Overview :
Recombinant protein from the full-length sequence of Homo sapiens C-X-C motif chemokine ligand 11 (CXCL11), transcript variant 1 (NM_005409), with a DYKDDDDK tag was expressed in human cells.
Description :
Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. This antimicrobial gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. Two transcript variants encoding different isoforms have been found for this gene.
Source :
Human Cells
Species :
Human
Tag :
DYKDDDDK
Molecular Mass :
8.3 kDa
Endotoxin :
< 0.1 ng/μg of protein (< 1 EU/μg)
Purity :
> 90% by SDS-PAGE gel and Coomassie Blue staining
Applications :
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Storage Buffer :
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.