Human CXCL11, Biotin-tagged CXCL11-106H

Human CXCL11, Biotin-tagged


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Human CXCL11, Biotin-tagged

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Cat.No. : CXCL11-106H Optional Service: Optional requirements on this protein
Product Overview : It is a synthetic Protein with Biotin tag.
Description : Interferon-inducible T cell a chemoattractant (ITAC), which is also known as SCYB9B, -R1 or H174, is a non-ELR CXC chemokine. ITAC"s cDNA encodes a 94 amino acid precursor with a 21 amino acid putative signal sequence which is cleaved to form the mature 73 amino acid protein. ITAC shares 36% and 37% sequence homology with IP-10 and MIG, respectively. ITAC is expressed at low levels in normal tissues including the thymus, spleen and pancreas. The expression of ITAC mRNA is radically up regulated in interferon- and IL-1 stimulated astrocytes. Moderate increases in expression are also observed in stimulated monocytes. ITAC possesses potent chemoattractant activity for IL-2 activated T-cells and transfected cell lines expressing CXCR3 receptors, but not freshly isolated T-cells, neutrophils or monocytes. The gene which encodes ITAC has been mapped to chromosome 4.
Species : Human
Tag : Biotin
Form : Lyophilized
Applications : Activity Assay
Storage : Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
Reconstitution : Recommended reconstitution in sterile phosphate buffered saline which contains at least 0.1% human or bovine serum albumin to prepare a stocksolution of no less than 20 μg/ml and vortex thoroughly.
Gene Name : CXCL11 chemokine (C-X-C motif) ligand 11 [ Homo sapiens ]
Official Symbol : CXCL11
Synonyms : CXCL11; chemokine (C-X-C motif) ligand 11; SCYB9B, SCYB11, small inducible cytokine subfamily B (Cys X Cys), member 11; C-X-C motif chemokine 11; b R1; H174; I TAC; IP 9; beta-R1; small inducible cytokine B11; small-inducible cytokine B11; interferon gamma-inducible protein 9; interferon-inducible T-cell alpha chemoattractant; small inducible cytokine subfamily B (Cys-X-Cys), member 11; small inducible cytokine subfamily B (Cys-X-Cys), member 9B; IP9; IP-9; b-R1; I-TAC; SCYB11; SCYB9B; MGC102770;
Gene ID : 6373
mRNA Refseq : NM_005409
Protein Refseq : NP_005400
MIM : 604852
UniProt ID : O14625
Chromosome Location : 4q21
Pathway : CXCR3-mediated signaling events, organism-specific biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem;
Function : chemokine activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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