Human CXCL11, Biotin-tagged
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Cat.No. : | CXCL11-106H Optional Service: Optional requirements on this protein |
Product Overview : | It is a synthetic Protein with Biotin tag. |
Description : | Interferon-inducible T cell a chemoattractant (ITAC), which is also known as SCYB9B, -R1 or H174, is a non-ELR CXC chemokine. ITAC"s cDNA encodes a 94 amino acid precursor with a 21 amino acid putative signal sequence which is cleaved to form the mature 73 amino acid protein. ITAC shares 36% and 37% sequence homology with IP-10 and MIG, respectively. ITAC is expressed at low levels in normal tissues including the thymus, spleen and pancreas. The expression of ITAC mRNA is radically up regulated in interferon- and IL-1 stimulated astrocytes. Moderate increases in expression are also observed in stimulated monocytes. ITAC possesses potent chemoattractant activity for IL-2 activated T-cells and transfected cell lines expressing CXCR3 receptors, but not freshly isolated T-cells, neutrophils or monocytes. The gene which encodes ITAC has been mapped to chromosome 4. |
Species : | Human |
Tag : | Biotin |
Form : | Lyophilized |
AA Sequence : | FPMFKRGRCL CIGPGVKAVK VADIEKASIM YPSNNCDKIE VIITLKENKG QRCLNPKSKQ ARLIIKKVER KNF (Biotin conjugated to C-terminus) |
Applications : | Activity Assay |
Storage : | Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles |
Reconstitution : | Recommended reconstitution in sterile phosphate buffered saline which contains at least 0.1% human or bovine serum albumin to prepare a stocksolution of no less than 20 μg/ml and vortex thoroughly. |
Gene Name : | CXCL11 chemokine (C-X-C motif) ligand 11 [ Homo sapiens ] |
Official Symbol : | CXCL11 |
Synonyms : | CXCL11; chemokine (C-X-C motif) ligand 11; SCYB9B, SCYB11, small inducible cytokine subfamily B (Cys X Cys), member 11; C-X-C motif chemokine 11; b R1; H174; I TAC; IP 9; beta-R1; small inducible cytokine B11; small-inducible cytokine B11; interferon gamma-inducible protein 9; interferon-inducible T-cell alpha chemoattractant; small inducible cytokine subfamily B (Cys-X-Cys), member 11; small inducible cytokine subfamily B (Cys-X-Cys), member 9B; IP9; IP-9; b-R1; I-TAC; SCYB11; SCYB9B; MGC102770; |
Gene ID : | 6373 |
mRNA Refseq : | NM_005409 |
Protein Refseq : | NP_005400 |
MIM : | 604852 |
UniProt ID : | O14625 |
Chromosome Location : | 4q21 |
Pathway : | CXCR3-mediated signaling events, organism-specific biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; |
Function : | chemokine activity; |
◆ Recombinant Protein
CCL11-01H | Recombinant Human CXCL11 Protein, DYKDDDDK-tagged | +Inquiry |
Cxcl11-2386M | Recombinant Mouse Cxcl11 Protein | +Inquiry |
Cxcl11-2773H | Recombinant Hamster Cxcl11 Protein, His-tagged | +Inquiry |
CXCL11-57H | Recombinant Human CXCL11 Protein | +Inquiry |
CXCL11-931R | Recombinant Rhesus Macaque CXCL11 Protein, His (Fc)-Avi-tagged | +Inquiry |
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◆ Lysates
CXCL11-7171HCL | Recombinant Human CXCL11 293 Cell Lysate | +Inquiry |
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CXCL1Cxcl10CXCL11CXCL12CXCL13CXCL14Cxcl15Cxcl16Cxcl2CXCL3Cxcl5CXCL6CXCL9Cxcl17CXCL7
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