CXCL11
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Official Full Name
chemokine (C-X-C motif) ligand 11
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Background
Chemokine (C-X-C motif); ligand 11 (CXCL11); is a small cytokine belonging to the CXC chemokine family that is also called Interferon-inducible T-cell alpha chemoattractant (I-TAC); and Interferon-gamma-inducible protein 9 (IP-9);. It is highly expressed -
Synonyms
CXCL11; chemokine (C-X-C motif) ligand 11; SCYB9B, SCYB11, small inducible cytokine subfamily B (Cys X Cys), member 11; C-X-C motif chemokine 11; b R1; H174; I TAC; IP 9; beta-R1; small inducible cytokine B11; small-inducible cytokine B11; interferon gam;
- Involved Pathway
- Protein Function
- Interacting Protein
- CXCL11 Related Gene Family
- CXCL11 Related Research Area
CXCL11 involved in several pathways and played different roles in them. We selected most pathways CXCL11 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, Toll-like receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CXCL11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cytokine-cytokine receptor interaction | TGFB2;CRLF2;BMPR1AA;CSF1R;CCL3L1;CCL11;TNFSF10;LIF;CD40LG |
| Chemokine signaling pathway | GNAI2;GNG7;CCR1L1;JAK3;Adcy4;DOCK2;ADRBK2;NRAS;PRKACG |
| Toll-like receptor signaling pathway | CCL3L1;FADD;RELA;CCL4;IFNAR2;RAC1B;TLR2-2;IRF5;IRF3 |
CXCL11 has several biochemical functions, for example, CXCR3 chemokine receptor binding, chemokine activity, heparin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CXCL11 itself. We selected most functions CXCL11 had, and list some proteins which have the same functions with CXCL11. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| CXCR3 chemokine receptor binding | CXCL11.8;CXCL10;CXCL11;CXCL9;CXCL13;PF4 |
| chemokine activity | CXCL3;CXCL8B.3;CCL34B.9;CCL8;CXCL11;C5;Cxcl15;CCL11;CCL19 |
| heparin binding | EPYC;CXCL13;PCOLCE;CTGFA;ADAMTS3;MMP7;MSTN;PRG2;WISP1A |
| protein binding | PHF10;ZDHHC17;LINGO1B;PITPNM1;KIAA1967;DBC1;pab1;MYRIP;GATA1 |
CXCL11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CXCL11 here. Most of them are supplied by our site. Hope this information will be useful for your research of CXCL11.
DPP4; MTUS2; LRRK2; DPP8; dedA3
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