Recombinant Human DARC Protein

• Cat.No.: DARC-26807H
• Product Overview: Recombinant human DARC protein without tag was expressed in Wheat Germ(in vitro).

Specification

• Description: The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system. Two transcript variants encoding different isoforms have been found for this gene.
• Source: Wheat Germ
• Species: Human
• Molecular Mass: 35.6 kDa
• AA Sequence: MGNCLHRAELSPSTENSSQLDFEDV WNSSYGVNDSFPDGDYGANLEAAAP CHSCNLLDDSALPFFILTSVLGILA SSTVLFMLFRPLFRWQLCPGWPVLA QLAVGSALFSIVVPVLAPGLGSTRS SALCSLGYCVWYGSAFAQALLLGCH ASLGHRLGAGQVPGLTLGLTVGIWG VAALLTLPVTLASGASGGLCTLIYS TELKALQATHTVACLAIFVLLPLGL FGAKGLKKALGMGPGPWMNILWAWF IFWWPHGVVLGLDFLVRSKLLLLST CLAQQALDLLLNLAEALAILHCVAT PLLLALFCHQATRTLLPSLPLPEGW SSHLDTLGSKS
• Applications: AP
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 25 mM Tris-HCl of pH8.0 containing 2% glycerol

Gene Information

• Gene Name: ACKR1 atypical chemokine receptor 1 (Duffy blood group) [ Homo sapiens (human) ]
• Official Symbol: DARC
• Synonyms: ACKR1; atypical chemokine receptor 1 (Duffy blood group); FY; Dfy; GPD; DARC; GpFy; CCBP1; CD234; WBCQ1; DARC/ACKR1; atypical chemokine receptor 1; Duffy antigen chemokine receptor; Duffy blood group antigen; Duffy blood group system protein; Duffy blood group, chemokine receptor; Fy glycoprotein; glycoprotein D; plasmodium vivax receptor
• Gene ID: 2532
• mRNA Refseq: NM_001122951
• Protein Refseq: NP_001116423
• MIM: 613665
• UniProt ID: Q16570