Recombinant Human DOT1L Protein, GST-tagged


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Recombinant Human DOT1L Protein, GST-tagged

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Cat.No. : DOT1L-006H
Product Overview : Recombinant Human DOT1L protein (2-416) with a N-terminal GST-tag was expressed in E. coli.
Description : The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes.
Source : E. coli
Species : Human
Tag : GST
Molecular Mass : 74.1 kDa
Protein length : 2-416
Purity : ≥95% estimated by SDS-PAGE
Stability : ≥ 6 months
Storage : -80 centigrade
SDS-PAGE Analysis of DOT1L :

Lane 1: MW Markers
Lane 2: DOT1L (1 μg)
Lane 3: DOT1L (2 μg)
Lane 4: DOT1L (4 μg)

Gene Name : DOT1L DOT1 like histone lysine methyltransferase [ Homo sapiens (human) ]
Official Symbol : DOT1L
Synonyms : DOT1L; DOT1 like histone lysine methyltransferase; DOT1; KMT4; histone-lysine N-methyltransferase, H3 lysine-79 specific; DOT1 like histone H3K79 methyltransferase; DOT1-like histone methyltransferase
DOT1-like protein; DOT1-like, histone H3 methyltransferase; H3-K79-HMTase; histone H3-K79 methyltransferase; histone methyltransferase DOT1L; lysine N-methyltransferase 4; EC
Gene ID : 84444
mRNA Refseq : NM_032482
Protein Refseq : NP_115871
MIM : 607375
UniProt ID : Q8TEK3
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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