Recombinant Human DOT1L Protein, GST-tagged DOT1L-006H

Recombinant Human DOT1L Protein, GST-tagged

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Recombinant Human DOT1L Protein, GST-tagged

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Cat.No. : DOT1L-006H
Product Overview : Recombinant Human DOT1L protein (2-416) with a N-terminal GST-tag was expressed in E. coli.
Description : The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes.
Source : E. coli
Species : Human
Tag : GST
Molecular Mass : 74.1 kDa
Protein length : 2-416
Purity : ≥95% estimated by SDS-PAGE
Stability : ≥ 6 months
Storage : -80 centigrade
SDS-PAGE Analysis of DOT1L :

Lane 1: MW Markers
Lane 2: DOT1L (1 μg)
Lane 3: DOT1L (2 μg)
Lane 4: DOT1L (4 μg)

Gene Name : DOT1L DOT1 like histone lysine methyltransferase [ Homo sapiens (human) ]
Official Symbol : DOT1L
Synonyms : DOT1L; DOT1 like histone lysine methyltransferase; DOT1; KMT4; histone-lysine N-methyltransferase, H3 lysine-79 specific; DOT1 like histone H3K79 methyltransferase; DOT1-like histone methyltransferase
DOT1-like protein; DOT1-like, histone H3 methyltransferase; H3-K79-HMTase; histone H3-K79 methyltransferase; histone methyltransferase DOT1L; lysine N-methyltransferase 4; EC 2.1.1.360
Gene ID : 84444
mRNA Refseq : NM_032482
Protein Refseq : NP_115871
MIM : 607375
UniProt ID : Q8TEK3

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