Recombinant Human EPHA2 Protein, GST-tagged

• Cat.No.: EPHA2-3378H
• Product Overview: Human EPHA2 full-length ORF ( NP_004422.2, 1 a.a. - 976 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.[provided by RefSeq, May 2010]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 134.7 kDa
• AA Sequence: MELQAARACFALLWGCALAAAAAAQ GKEVVLLDFAAAGGELGWLTHPYGK GWDLMQNIMNDMPIYMYSVCNVMSG DQDNWLRTNWVYRGEAERIFIELKF TVRDCNSFPGGASSCKETFNLYYAE SDLDYGTNFQKRLFTKIDTIAPDEI TVSSDFEARHVKLNVEERSVGPLTR KGFYLAFQDIGACVALLSVRVYYKK CPELLQGLAHFPETIAGSDAPSLAT VAGTCVDHAVVPPGGEEPRMHCAVD GEWLVPIGQCLCQAGYEKVEDACQA CSPGFFKFEASESPCLECPEHTLPS PEGATSCECEEGFFRAPQDPASMPC TRPPSAPHYLTAVGMGAKVELRWTP PQDSGGREDIVYSVTCEQCWPESGE CGPCEASVRYSEPPHGLTRTSVTVS DLEPHMNYTFTVEARNGVSGLVTSR SFRTASVSINQTEPPKVRLEGRSTT SLSVSWSIPPPQQSRVWKYEVTYRK KGDSNSYNVRRTEGFSVTLDDLAPD TTYLVQVQALTQEGQGAGSKVHEFQ TLSPEGSGNLAVIGGVAVGVVLLLV LAGVGFFIHRRRKNQRARQSPEDVY FSKSEQLKPLKTYVDPHTYEDPNQA VLKFTTEIHPSCVTRQKVIGAGEFG EVYKGMLKTSSGKKEVPVAIKTLKA GYTEKQRVDFLGEAGIMGQFSHHNI IRLEGVISKYKPMMIITEYMENGAL DKFLREKDGEFSVLQLVGMLRGIAA GMKYLANMNYVHRDLAARNILVNSN LVCKVSDFGLSRVLEDDPEATYTTS GGKIPIRWTAPEAISYRKFTSASDV WSFGIVMWEVMTYGERPYWELSNHE VMKAINDGFRLPTPMDCPSAIYQLM MQCWQQERARRPKFADIVSILDKLI RAPDSLKTLADFDPRVSIRLPSTSG SEGVPFRTVSEWLESIKMQQYTEHF MAAGYTAIEKVVQMTNDDIKRIGVR LPGHQKRIAYSLLGLKDQVNTVGIP I
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: EPHA2 EPH receptor A2 [ Homo sapiens ]
• Official Symbol: EPHA2
• Synonyms: EPHA2; EPH receptor A2; ECK, EphA2; ephrin type-A receptor 2; soluble EPHA2 variant 1; tyrosine-protein kinase receptor ECK; epithelial cell receptor protein tyrosine kinase; ECK; CTPA; ARCC2; CTPP1
• Gene ID: 1969
• mRNA Refseq: NM_004431
• Protein Refseq: NP_004422
• MIM: 176946
• UniProt ID: P29317