Recombinant Human Ephrin-A1
Cat.No. : | EFNA1-150H |
Product Overview : | Recombinant Human Ephrin A1 protein expressed inE.coliencodes full length amino acids and has a molecular mass of 47 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | EFNA1-150H |
Description : | Ephrins are a family of molecules which bind to tyrosine kinase receptor Eph. The Eph receptor and their membrane-attached ligands, ephrins, show diverse expression patterns during development. The crucial roles of Eph and ephrins during development suggest involvement of these genes in congenital disorders affecting the nervous system and other tissues. Eph receptors and ephrins may be involved in carcinogenesis. |
Source : | Recombinant Human full length Ephrin A1 protein expressed inE.coli. |
Formulation : | 5µg/50µl Recombinant Human Ephrin A1 protein at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol. |
Application and suggested dilutions : | •ELISA•Inhibition Assays •Western Blotting |
Characterization : | On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 47 kDa (Including GST). |
Storage & stability : | Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stable for 12 months. |
Publication : |
The Small Molecule Ephrin Receptor Inhibitor, GLPG1790, Reduces Renewal Capabilities of Cancer Stem Cells, Showing Anti-Tumour Efficacy on Preclinical Glioblastoma Models (2019)
|
Gene Name : | EFNA1 ephrin-A1 [ Homo sapiens ] |
Synonyms : | EFNA1; B61; ECKLG; EFL1; EPLG1; LERK-1; TNFAIP4; Ephrin-A1; OTTHUMP00000033242; OTTHUMP00000033271; EPH-related receptor tyrosine kinase ligand 1; Immediate early response protein B61; Tumor necrosis factor, alpha-induced protein 4; Ligand of eph-related kinase 1 |
Gene ID : | 1942 |
mRNA Refseq : | NM_004428 |
Protein Refseq : | NP_004419 |
MIM : | 191164 |
UniProt ID : | P20827 |
Chromosome Location : | 1q21-q22 |
Pathway : | Axon guidance |
Function : | Ephrin receptor binding |
Products Types
◆ Recombinant Protein | ||
EFNA1-1681R | Recombinant Rat EFNA1 Protein, His (Fc)-Avi-tagged | +Inquiry |
EFNA1-469R | Recombinant Rat EFNA1 Protein (18-182 aa), GST-tagged | +Inquiry |
Efna1-2753M | Recombinant Mouse Efna1 Protein, Myc/DDK-tagged | +Inquiry |
EFNA1-1382M | Recombinant Mouse EFNA1 Protein, Fc/His-tagged | +Inquiry |
Efna1-3314M | Active Recombinant Mouse Efna1 protein(Met1-Ser182), His-tagged | +Inquiry |
◆ Lysates | ||
EFNA1-1514RCL | Recombinant Rat EFNA1 cell lysate | +Inquiry |
EFNA1-2177MCL | Recombinant Mouse EFNA1 cell lysate | +Inquiry |
EFNA1-2594HCL | Recombinant Human EFNA1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionYes, EFNA1 is being investigated as a potential therapeutic target in cancer treatment, aiming to develop drugs that modulate its activity.
Researchers are exploring the use of EFNA1 as a biomarker for cancer detection, with studies suggesting its potential as a diagnostic tool.
EFNA1 binds to Eph receptors, initiating cell signaling pathways that regulate various cellular processes, making this interaction crucial for normal physiological functions.
EFNA1 is implicated in cancer progression, influencing cell migration and invasion. Understanding its role can potentially lead to targeted therapies for certain cancers.
Dysregulation of EFNA1 has been linked to certain neurological disorders, including Alzheimer's disease and neurodevelopmental disorders.
Customer Reviews (3)
Write a reviewTheir prompt assistance and willingness to go above and beyond to ensure my success have been immensely valuable.
Its purity, stability, and consistency are unparalleled, ensuring reliable and reproducible results in my research.
This protein has proven to be an invaluable asset in my experiments, enabling accurate and precise measurements with exceptional sensitivity.
Ask a Question for All EFNA1 Products
Required fields are marked with *
My Review for All EFNA1 Products
Required fields are marked with *
Inquiry Basket