Efna1

  • Official Full Name

    ephrin-A1

  • Overview

    This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system
  • Synonyms

    EFNA1; ephrin-A1; EPLG1, TNFAIP4; ECKLG; LERK1; TNF alpha-induced protein 4; ligand of eph-related kinase 1; immediate early response protein B61; eph-related receptor tyrosine kinase ligand 1; tumor necrosis factor alpha-induced protein 4; tumor necrosis; B61; EFL1; EPLG1; LERK-1; TNFAIP4;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Human
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Yeast
  • C
  • Fc
  • hFc
  • His
  • Fc|His
  • GST
  • His (Fc)
  • Avi
  • SUMO
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EFNA1-150H Recombinant Human Ephrin-A1 E.coli N/A
Human EFNA1-357H Active Recombinant Human EFNA1 Protein, His-tagged HEK293 His Met 1-Ser182
Human EFNA1-2238H Recombinant Human EFNA1, His tagged Human Cell His
Human EFNA1-355H Recombinant Human EFNA1 Protein, Fc-tagged HEK293 Fc
Human EFNA1-2060H Recombinant Human Ephrin-A1, Fc Chimera Mammalian Cell Fc
Human EFNA1-3096H Recombinant Human EFNA1 Protein, GST-tagged Wheat Germ GST
Human EFNA1-1279H Recombinant Human Ephrin-A1, His-tagged Human His
Human EFNA1-2326H Recombinant Human EFNA1, Fc-His tagged Human Cell Fc/His
Human EFNA1-4190H Recombinant Human EFNA1 protein, His-tagged E.coli His
Human EFNA1-28470TH Recombinant Human EFNA1, His-tagged E.coli His 164 amino acids
Human EFNA1-28581TH Recombinant Human EFNA1 Wheat Germ N/A 205 amino acids
Human EFNA1-2594HCL Recombinant Human EFNA1 cell lysate Human Cell N/A
Human EFNA1-1561H Recombinant Human EFNA1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human EFNA1-328H Active Recombinant Human EFNA1 protein, hFc-tagged HEK293 hFc Met1-Ser182
Human EFNA1-229H Recombinant Human EFNA1 Protein, Fc-tagged HEK293 Fc 205
Human EFNA1-136HF Recombinant Full Length Human EFNA1 Protein In Vitro Cell Free System 205 amino acids
Human EFNA1-4215HF Recombinant Full Length Human EFNA1 Protein, GST-tagged In Vitro Cell Free System GST 205 amino acids
Human EFNA1-1407H Recombinant Human EFNA1 protein, Fc-tagged HEK293 Fc Asp19-Ser182
Human EFNA1-2032H Recombinant Human EFNA1 Protein (Asp19-Ser182), N-His tagged E.coli N-His Asp19-Ser182
Human EFNA1-1386H Recombinant Human EFNA1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human EFNA1-3265H Recombinant Human EFNA1 Protein (Asp19-Ser182), C-His tagged Mammalian cells C-His Asp19-Ser182
Human EFNA1-301377H Recombinant Human EFNA1 protein, GST-tagged E.coli GST Asp56-Ser105
Human EFNA1-3264H Recombinant Human EFNA1 Protein (Asp19-Ser182), C-Fc tagged Mammalian cells C-Fc Asp19-Ser182
Human EFNA1-2836H Recombinant Human EFNA1 protein, His-SUMO-tagged E.coli His-SUMO 19-182aa
Mouse Efna1-425M Active Recombinant Mouse Ephrin A1, His-tagged Mammalian cells His
Mouse Efna1-3264M Active Recombinant Mouse Efna1 protein(Met1-Ser182), hFc-tagged HEK293 C-hFc Met1-Ser182
Mouse Efna1-1730M Recombinant Mouse Ephrin A1, Fc-His Mammalian cells Fc/His
Mouse Efna1-3314M Active Recombinant Mouse Efna1 protein(Met1-Ser182), His-tagged HEK293 C-His Met1-Ser182
Mouse EFNA1-2177MCL Recombinant Mouse EFNA1 cell lysate Human Cell N/A
Mouse Efna1-159M Recombinant Mouse Efna1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse EFNA1-1382M Recombinant Mouse EFNA1 Protein, Fc/His-tagged HEK293 Fc/His
Mouse Efna1-159M-B Recombinant Mouse Efna1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Efna1-2753M Recombinant Mouse Efna1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat EFNA1-2024R Recombinant Rat EFNA1 Protein Mammalian Cell His
Rat Efna1-7438R Active Recombinant Rat Efna1 protein(Met1-His181), His-tagged HEK293 C-His Met1-His181
Rat EFNA1-1514RCL Recombinant Rat EFNA1 cell lysate Human Cell N/A
Rat EFNA1-469R Recombinant Rat EFNA1 Protein (18-182 aa), GST-tagged E.coli GST 18-182 aa
Rat Efna1-2837R Recombinant Rat Efna1 protein, His-tagged E.coli His 18-182aa
Rat EFNA1-1681R-B Recombinant Rat EFNA1 Protein Pre-coupled Magnetic Beads HEK293
Rat EFNA1-1383R Recombinant Rat EFNA1 Protein (18-182 aa), His-tagged Yeast His 18-182 aa
Rat EFNA1-1681R Recombinant Rat EFNA1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Efna1 Related Articles
  • Efna1 Related Research Area

Efna1 involved in several pathways and played different roles in them. We selected most pathways Efna1 participated on our site, such as Arf6 signaling events, Axon guidance, Developmental Biology, which may be useful for your reference. Also, other proteins which involved in the same pathway with Efna1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Arf6 signaling eventsEFNA1;GULP1;IPCEF1;ARAP2;EGFR;ADRB2;ADAP1;KIF13B;AGTR1
Axon guidanceJAK2;NRP2;DUSP4;PHB;SIAH2;PTPRA;ROBO1;L1CAM;EGF
Developmental BiologyRHOC;DLG3;BOC;DPYSL5B;ANK2B;CAP2;EFNA3B;FGF10B;CDK5R1B
EPH-Ephrin signalingAP2S1;AP2M1;EFNA1B;EFNB2A;KDR;CLTB;EPHA4A;KALRNB;CFL1
EPH-ephrin mediated repulsion of cellsEPHB3A;CLTB;EFNB2A;EFNA1A;AP2B1;EFNA3;EFNB3B;EFNA5;EFNB2
EPHA forward signalingEFNA1;ARHGEF15;EPHA2;CRKL;EFNA3;EFNA2;EFNA5;BLK
EPHA-mediated growth cone collapseEPHA10;EFNA1A;MYL9;EPHA4A;KDR;EFNA3B;SHB;EFNA2;EFNA4
EPHA2 forward signaling

Efna1 has several biochemical functions, for example, ephrin receptor binding, protein binding, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Efna1 itself. We selected most functions Efna1 had, and list some proteins which have the same functions with Efna1. You can find most of the proteins on our site.

Function Related Protein
ephrin receptor bindingEPHA7;EFNA1;EFNB2;EFNA2;ANKS1B;EFNA3;EFNA1B;EFNB2A;FYN
protein bindingMKNK2;CD9;VBP1;KHDC1B;KREMEN1;ADAMTS10;AP3S1;CRH;CASP6
receptor bindingPLG;ABL2;CSNK2B;CCL13;CRTAM;REN;AGRP2;HTT;HACL1

Efna1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Efna1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Efna1.

EPHA2; PPBP; XRCC6; EEF1G; SUMO2; KAT5

Miao, H; Gale, NW; et al. EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties. ONCOGENE 34:558-567(2015).
McKinney, N; Yuan, LP; et al. EphrinB1 expression is dysregulated and promotes oncogenic signaling in medulloblastoma. JOURNAL OF NEURO-ONCOLOGY 121:109-118(2015).
  • Q&As
  • Reviews

Q&As (5)

Ask a question
Can EFNA1 be a target for therapeutic interventions in cancer treatment? 05/06/2021

Yes, EFNA1 is being investigated as a potential therapeutic target in cancer treatment, aiming to develop drugs that modulate its activity.

Are there diagnostic applications for EFNA1 in cancer detection? 01/15/2021

Researchers are exploring the use of EFNA1 as a biomarker for cancer detection, with studies suggesting its potential as a diagnostic tool.

How does EFNA1 interact with the Eph receptors, and what is the significance of this interaction? 04/16/2019

EFNA1 binds to Eph receptors, initiating cell signaling pathways that regulate various cellular processes, making this interaction crucial for normal physiological functions.

How does EFNA1 impact cancer research and treatment? 02/02/2018

EFNA1 is implicated in cancer progression, influencing cell migration and invasion. Understanding its role can potentially lead to targeted therapies for certain cancers.

Are there any neurological disorders associated with EFNA1 dysregulation? 10/26/2016

Dysregulation of EFNA1 has been linked to certain neurological disorders, including Alzheimer's disease and neurodevelopmental disorders.

Customer Reviews (3)

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Reviews
08/15/2019

    Their prompt assistance and willingness to go above and beyond to ensure my success have been immensely valuable.

    04/04/2019

      Its purity, stability, and consistency are unparalleled, ensuring reliable and reproducible results in my research.

      11/22/2016

        This protein has proven to be an invaluable asset in my experiments, enabling accurate and precise measurements with exceptional sensitivity.

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