Recombinant Human FTO Protein, MYC/DDK-tagged

• Cat.No.: FTO-2663H
• Product Overview: Recombinant Human FTO protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Description: This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 58.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: FTO fat mass and obesity associated [ Homo sapiens ]
• Official Symbol: FTO
• Synonyms: ALKBH9; BMIQ14; GDFD
• Gene ID: 79068
• mRNA Refseq: NM_001080432
• Protein Refseq: NP_001073901
• MIM: 610966
• UniProt ID: Q9C0B1