Recombinant Human FTO protein, His-tagged

• Cat.No.: FTO-28954TH
• Product Overview: Recombinant Human FTO(aa 2-505) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 2-505 a.a.
• Form: Liquid. 0.2μm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl.
• Molecular Mass: ~65kDa (SDS-PAGE)
• Endotoxin: <1EU/μg purified protein (LAL test; Lonza).
• Purity: ≥90% (SDS-PAGE)
• Stability: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Working aliquots are stable for up to 3 months when stored at -20 centigrade.
• Storage: Short Term Storage: +4 centigradeLong Term Storage: -20 centigrade
• Concentration: 0.2mg/ml

Gene Information

• Gene Name: FTO fat mass and obesity associated [ Homo sapiens ]
• Official Symbol: FTO
• Synonyms: FTO; fat mass and obesity associated; alpha-ketoglutarate-dependent dioxygenase FTO; KIAA1752; MGC5149; protein fto; fat mass and obesity-associated protein
• Gene ID: 79068
• mRNA Refseq: NM_001080432
• Protein Refseq: NP_001073901
• MIM: 610966
• UniProt ID: Q9C0B1
• Chromosome Location: 16q12.2
• Function: DNA-N1-methyladenine dioxygenase activity; ferrous iron binding; metal ion binding; oxidative DNA demethylase activity; oxidative RNA demethylase activity; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen