Recombinant Human GAPDH, GST-tagged
Cat.No. : | GAPDH-117H |
Product Overview : | Human GAPDH full-length ORF (1 a.a. - 335 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The enzyme exists as a tetramer of identical chains. Many pseudogenes similar to this locus are present in the human genome. Two transcript variants encoding different isoforms have been found for this gene. |
Source : | Wheat germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 62.59 kDa |
AA Sequence : | MGKVKVGVNGFGRIGRLVTRAAFNS GKVDIVAINDPFIDLNYMVYMFQYD STHGKFHGTVKAENGKLVINGNPIT IFQERDPSKIKWGDAGAEYVVESTG VFTTMEKAGAHLQGGAKRVIISAPS ADAPMFVMGVNHEKYDNSLKIISN ASCTTNCLAPLAKVIHDNFGIVEGL MTTVHAITATQKTVDGPSGKLWRDG R GALQNIIPASTGAAKAVGKVIPE LNGKLTGMAFRVPTANVSVVDLTCR LEKPAKYDDIKKVVKQASEGPLKGI LGYTEHQVVSSDFNSDTHSSTFDAG AG IALNDHFVKLISWYDNEFGYSNRVV DLMAHMASKE |
Applications : | ELISA; WB-Re; AP; Array |
Storage : | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | GAPDH glyceraldehyde-3-phosphate dehydrogenase [ Homo sapiens (human) ] |
Official Symbol : | GAPDH |
Synonyms : | GAPDH; G3PD; GAPD; glyceraldehyde-3-phosphate dehydrogenase; aging-associated gene 9 protein; peptidyl-cysteine S-nitrosylase GAPDH; EC 1.2.1.12 |
Gene ID : | 2597 |
mRNA Refseq : | NM_002046 |
Protein Refseq : | NP_002037 |
MIM : | 138400 |
UniProt ID : | P04406 |
Chromosome Location : | 12p13 |
Pathway : | Alzheimer''s disease; Biosynthesis of amino acids; Carbon metabolism |
Function : | NAD binding; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity; identical protein binding |
Products Types
◆ Recombinant Protein | ||
Gapdh-1562R | Recombinant Rat Gapdh Protein, His-tagged | +Inquiry |
Gapdh-505M | Recombinant Mouse Gapdh protein(Met1-Glu333), His-tagged | +Inquiry |
GAPDH-959H | Recombinant Human GAPDH Protein, His (Fc)-Avi-tagged | +Inquiry |
GAPDH-014H | Recombinant Human GAPDH Protein(Met 1-Glu 335), His-tagged | +Inquiry |
GAPDH-517C | Recombinant Chicken GAPDH Protein (2-333 aa), His-tagged | +Inquiry |
◆ Native Protein | ||
GAPDH-62H | Native Human Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) | +Inquiry |
GAPDH-126R | Active Native Rabbit Glyceraldehyde-3-phosphate Dehydrogenase | +Inquiry |
◆ Lysates | ||
GAPDH-6024HCL | Recombinant Human GAPDH 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-2216 | GAPDH Activity Assay Kit | +Inquiry |
Related Gene
Not For Human Consumption!
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Customer Reviews (3)
Write a reviewCustomer service was patient, prompt and accurate in answering my queries.
High protein concentration, good quality, worth buying!
The product brochure is very detailed and has comprehensive basic information about the GAPDH protein.
Q&As (5)
Ask a questionGAPDH is highly expressed in all tissues with relatively stable expression and is often used as an internal reference protein.
GAPDH is closely related to the study of hepatocellular carcinoma and can be used as one of the indicators for the diagnosis of hepatocellular carcinoma.
GAPDH binds to HDAC1.
GAPDH binds to matrix proteins, regulates host immune responses, and plays a role in pathogen virulence and surface localization, among others.
Interference with GAPDH protein expression results in telomere shortening.
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