Recombinant Human GPC3 Protein, Fc-tagged

Cat.No. : GPC3-270H
Product Overview : Recombinant human GPC3 protein with Fc tag was expressed in HEK293.
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Description : Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.
Source : HEK293
Species : Human
Tag : Fc
Form : Lyophilized
Molecular Mass : 87.4 kDa
Protein Length : 580
AA Sequence : MAGTVRTACLVVAMLLSLDFPGQAQ PPPPPPDATCHQVRSFFQRLQPGLK WVPETPVPGSDLQVCLPKGPTCCSR KMEEKYQLTARLNMEQLLQSASMEL KFLIIQNAAVFQEAFEIVVRHAKNY TNAMFKNNYPSLTPQAFEFVGEFFT DVSLYILGSDINVDDMVNELFDSLF PVIYTQLMNPGLPDSALDINECLRG ARRDLKVFGNFPKLIMTQVSKSLQV TRIFLQALNLGIEVINTTDHLKFSK DCGRMLTRMWYCSYCQGLMMVKPCG GYCNVVMQGCMAGVVEIDKYWREYI LSLEELVNGMYRIYDMENVLLGLFS TIHDSIQYVQKNAGKLTTTIGKLCA HSQQRQYRSAYYPEDLFIDKKVLKV AHVEHEETLSSRRRELIQKLKSFIS FYSALPGYICSHSPVAENDTLCWNG QELVERYSQKAARNGMKNQFNLHEL KMKGPEPVVSQIIDKLKHINQLLRT MSMPKGRVLDKNLDEEGFESGDCGD DEDECIGGSGDGMIKVKNQLRFLAE LAYDLDVDDAPGNSQQATPKDNEIS TFHNLGNVHSPLKLLTSMAISVVCF FFLVH
Purity : > 98%
Applications : WB; ELISA; FACS; FC
Stability : This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
Storage : At -20 centigrade.
Concentration : 1 mg/mL
Storage Buffer : PBS (pH 7.4-7.5). Sterile-filtered colorless solution.
Reconstitution : Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.
Gene Name : GPC3 glypican 3 [ Homo sapiens (human) ]
Official Symbol : GPC3
Synonyms : GPC3; glypican 3; SDYS; glypican-3; DGSX; glypican proteoglycan 3; OCI 5; SGB; SGBS; SGBS1; secreted glypican-3; intestinal protein OCI-5; heparan sulphate proteoglycan; MXR7; OCI-5; GTR2-2;
Gene ID : 2719
mRNA Refseq : NM_001164617
Protein Refseq : NP_001158089
MIM : 300037
UniProt ID : P51654

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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08/12/2020

    The GPC3 protein offered by the manufacturer is of exceptional quality, making it an ideal choice to fulfill my experimental needs.

    09/18/2019

      The technical support provided by the manufacturer is invaluable in overcoming experimental hurdles and optimizing the utilization of GPC3 protein.

      04/10/2019

        Another crucial aspect where the manufacturer excels is their efficient supply chain management.

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