GPC3

  • Official Full Name

    glypican 3

  • Overview

    Glypican-3 (GPC3) is a glycosylphospatidyl inositol-anchored membrane protein, which may also be found in a secreted form. Recently, GPC3 was identified to be useful tumor marker for the diagnosis of HCC, hepatoblastoma, melanoma, testicular germ cell tum
  • Synonyms

    GPC3; glypican 3; SDYS; glypican-3; DGSX; glypican proteoglycan 3; OCI 5; SGB; SGBS; SGBS1; secreted glypican-3; intestinal protein OCI-5; heparan sulphate proteoglycan; MXR7; OCI-5; GTR2-2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • GMP Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chimpanzee
  • Cynomolgus
  • Cynomolgus monkey
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • CHO cells
  • E.coli
  • HEK293
  • Human Cell
  • In vitro E. coli expression system
  • Insect Cell
  • Mammalian cells
  • Wheat Germ
  • Yeast
  • C
  • 6His
  • Avi
  • His
  • Fc
  • GST
  • hFc
  • His (Fc)
  • Myc
  • His\Avi
  • His|GST
  • His|T7
  • human|IgG1|Fc
  • lFc
  • mFc
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GPC3-619H Active Recombinant Human GPC3, Fc-tagged, Biotinylated Human Cell Fc
Human GPC3-620H Active Recombinant Human GPC3, Fc-tagged Human Cell Fc
Human GPC3-338H Active Recombinant Human GPC3 Protein (Gln 25 - His 559), Fc-tagged, FITC-Labeled HEK293 Fc Gln 25 - His 559
Human GPC3-620HAF488 Active Recombinant Human GPC3 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc
Human GPC3-620HAF555 Active Recombinant Human GPC3 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc
Human GPC3-138H Active Recombinant Human GPC3 Protein(495S/A), hFc-tagged HEK293 hFc Met1-Ser550
Human GPC3-051H Active Recombinant Human GPC3 protein, His/Avi-tagged, Biotinylated CHO cells His/Avi Gln25-His559
Human GPC3-620HAF647 Active Recombinant Human GPC3 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc
Human GPC3-1514H Active Recombinant Human GPC3 protein, lFc-tagged HEK293 lFc Gln25-His559
Human GPC3-620HF Active Recombinant Human GPC3 Protein, Fc-tagged, FITC conjugated HEK293 Fc
Human GPC3-50H Recombinant Human GPC3 Yeast N/A
Human GPC3-2551H Active Recombinant Human GPC3 protein, His-tagged HEK293 His Met1-His559
Human GPC3-2246H Recombinant Human GPC3 protein (S359F), His-tagged, low endotoxin HEK293 His Gln25-His559
Human GPC3-27455TH Recombinant Human GPC3 Wheat Germ N/A 100 amino acids
Human GPC3-5683H Recombinant Human GPC3 protein, His & GST-tagged E.coli His/GST Thr343~His559 (Accession # P51654)
Human GPC3-2538HCL Recombinant Human GPC3 cell lysate Human Cell N/A
Human GPC3-2246HF Recombinant Human GPC3 Protein (S359F), His-tagged, low endotoxin, FITC conjugated HEK293 His Gln25-His559
Human GPC3-1259H Recombinant Human GPC3 protein, His-tagged E.coli His Thr343~His559
Human GPC3-620HP Recombinant Human GPC3 protein, Fc-tagged, R-PE labeled HEK293 Fc
Human GPC3-620HA Recombinant Human GPC3 protein, Fc-tagged, APC labeled HEK293 Fc
Human GPC3-2812H Recombinant Human GPC3 Protein (Ser359-Asn554), N-His tagged E.coli N-His Ser359-Asn554
Human GPC3-765H Active Recombinant Human GPC3 Transmembrane protein(VLPs) In vitro E. coli expression system N/A Gly510-Asn554
Human GPC3-2246HA Recombinant Human GPC3 protein, His-tagged, APC labeled Human Cell His
Human GPC3-2246HP Recombinant Human GPC3 protein, His-tagged, R-PE labeled Human Cell His
Human GPC3-4662H Active Recombinant Human GPC3 Protein, His-tagged, PE-Labeled HEK293 His Gln 25 - His 559
Human GPC3-766H Active Recombinant Human GPC3 Transmembrane protein(VLPs) HEK293 N/A Arg438-Asn554
Human GPC3-1456H Recombinant Human GPC3 protein, His-Myc-tagged HEK293 His/Myc 25-559aa
Human GPC3-14H Recombinant Human GPC3 Protein, C-6His-Avi tagged, Biotinylated Human Cell C-6His-Avi Gln25-His559
Human GPC3-4663H Active Recombinant Human GPC3 Protein, His-tagged, APC-Labeled HEK293 His Gln 25 - His 559
Human GPC3-4198H Recombinant Human GPC3 Protein (Met1-His559), C-His tagged Mammalian cells C-His Met1-His559
Human GPC3-186H Recombinant Human GPC3 Protein, His\Avi-tagged Human Cell His\Avi
Human GPC3-271H Recombinant Human GPC3 Protein, His-tagged HEK293 His 580
Human GPC3-621H Recombinant Human GPC3 Protein, Fc-tagged HEK293 Fc Gln 25 - His 559
Human GPC3-2246HAF488 Recombinant Human GPC3 Protein (S359F), His-tagged, low endotoxin, Alexa Fluor 488 conjugated HEK293 His Gln25-His559
Human GPC3-270H Recombinant Human GPC3 Protein, Fc-tagged HEK293 Fc 580
Human GPC3-5147H Recombinant Human GPC3 Protein, GST-tagged Wheat Germ GST
Human GPC3-2551HB Recombinant Human GPC3 protein, His-tagged, Biotinylated HEK293 His
Human GPC3-551HG Active GMP Recombinant Human GPC3 protein HEK293 DNA sequence encoding Human GPC3(NCBI Reference Sequence: NP_004475.1) was expressed with His tag at the C-terminal.
Human GPC3-22H Recombinant Human GPC3 Protein (25-559aa), C-His-tagged Insect Cell C-His 25-559
Human GPC3-2247H Active Recombinant Human GPC3 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Gln25-His559
Human GPC3-337H Active Recombinant Human GPC3 Protein (Gln 25 - His 559), Fc-tagged, low endotoxin HEK293 Fc Gln 25 - His 559
Human GPC3-336H Recombinant Human GPC3 Protein(495S/A), mFc-tagged HEK293 mFc Met1-Ser550
Human GPC3-2246HAF555 Recombinant Human GPC3 Protein (S359F), His-tagged, low endotoxin, Alexa Fluor 555 conjugated HEK293 His Gln25-His559
Human GPC3-2246HAF647 Recombinant Human GPC3 Protein (S359F), His-tagged, low endotoxin, Alexa Fluor 647 conjugated HEK293 His Gln25-His559
Mouse Gpc3-5627M Active Recombinant Mouse Gpc3, His-tagged Mammalian cells His
Mouse Gpc3-506M Active Recombinant Mouse Gpc3, His-tagged Insect Cell His Met1-Pro558
Mouse Gpc3-5684M Recombinant Mouse Gpc3 protein, His & T7-tagged E.coli His/T7 Ile344~Ser559 (Accession # Q8CFZ4)
Mouse Gpc3-120M Recombinant Mouse Gpc3 protein, Fc-tagged HEK293 human/IgG1/Fc 533
Mouse GPC3-001MCL Recombinant Mouse GPC3 cell lysate Insect Cell N/A
Mouse Gpc3-3824M-B Recombinant Mouse Gpc3 Protein Pre-coupled Magnetic Beads HEK293
Mouse Gpc3-1118M Recombinant Mouse Gpc3 protein, His-tagged HEK293 His Gln25-Met557
Mouse Gpc3-120MAF488 Recombinant Mouse Gpc3 Protein, hFc-tagged, Alexa Fluor 488 conjugated HEK293 hFc 533
Mouse Gpc3-120MAF555 Recombinant Mouse Gpc3 Protein, hFc-tagged, Alexa Fluor 555 conjugated HEK293 hFc 533
Mouse GPC3-1516M Active Recombinant Mouse GPC3 protein, Fc-tagged HEK293 Fc Gln25-Met557
Mouse Gpc3-272M Recombinant Mouse Gpc3 Protein, His-tagged HEK293 His 579
Mouse Gpc3-273M Recombinant Mouse Gpc3 Protein, Fc-tagged HEK293 Fc 579
Mouse Gpc3-120MF Recombinant Mouse Gpc3 Protein, hFc-tagged, FITC conjugated HEK293 hFc 533
Mouse Gpc3-3824M Recombinant Mouse Gpc3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Gpc3-120MA Recombinant Mouse Gpc3 protein, Fc-tagged, APC labeled HEK293 Fc
Mouse Gpc3-120MP Recombinant Mouse Gpc3 protein, Fc-tagged, R-PE labeled HEK293 Fc
Mouse Gpc3-120MAF647 Recombinant Mouse Gpc3 Protein, hFc-tagged, Alexa Fluor 647 conjugated HEK293 hFc 533
Rat GPC3-2633R Recombinant Rat Gpc3 protein, His-tagged E.coli His Ile344~Ser559
Rat Gpc3-5418R Recombinant Rat Gpc3 protein, His-tagged Yeast His 25-560aa
Rat GPC3-1305R Active Recombinant Rat GPC3 protein, His-tagged HEK293 His Gln25-Met557
Chimpanzee GPC3-5020C Recombinant Chimpanzee GPC3 protein, His-tagged HEK293 His 25-560aa
Cynomolgus GPC3-1517C Active Recombinant Cynomolgus GPC3 protein, Fc-tagged HEK293 Fc Gln25-His559
Cynomolgus GPC3-1515C Active Recombinant Cynomolgus GPC3 protein, lFc-tagged HEK293 lFc Gln25-His559
Cynomolgus GPC3-50C Recombinant Cynomolgus GPC3 protein, Fc-tagged HEK293 human/IgG1/Fc 535
Cynomolgus GPC3-50CAAF488 Recombinant Cynomolgus GPC3 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc 535
Cynomolgus GPC3-50CPAF647 Recombinant Monkey GPC3 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His Gln25-His559
Cynomolgus GPC3-1117C Recombinant Cynomolgus GPC3 protein, His-tagged HEK293 His Gln25-His559
Cynomolgus GPC3-50CAF Recombinant Cynomolgus GPC3 Protein, Fc-tagged, FITC conjugated HEK293 Fc 535
Cynomolgus GPC3-50CPAF488 Recombinant Monkey GPC3 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His Gln25-His559
Cynomolgus GPC3-50CPF Recombinant Monkey GPC3 Protein, His-tagged, FITC conjugated HEK293 His Gln25-His559
Cynomolgus GPC3-50CA Recombinant Cynomolgus GPC3 protein, Fc-tagged, APC labeled HEK293 Fc
Cynomolgus GPC3-50CAF488 Recombinant Cynomolgus GPC3 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc 535
Cynomolgus GPC3-50CF Recombinant Cynomolgus GPC3 Protein, Fc-tagged, FITC conjugated HEK293 Fc 535
Cynomolgus GPC3-50CAF647 Recombinant Cynomolgus GPC3 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc 535
Cynomolgus GPC3-50CPAF555 Recombinant Monkey GPC3 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His Gln25-His559
Cynomolgus GPC3-50CAF555 Recombinant Cynomolgus GPC3 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc 535
Cynomolgus GPC3-50CAAF647 Recombinant Cynomolgus GPC3 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc 535
Cynomolgus GPC3-50CAAF555 Recombinant Cynomolgus GPC3 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc 535
Cynomolgus GPC3-50CP Recombinant Cynomolgus GPC3 protein, Fc-tagged, R-PE labeled HEK293 Fc
Cynomolgus monkey GPC3-269C Recombinant Cynomolgus monkey GPC3 Protein, Fc-tagged HEK293 Fc 580
Cynomolgus monkey GPC3-268C Recombinant Cynomolgus monkey GPC3 Protein, His-tagged HEK293 His 580
Rhesus Macaque GPC3-1120R Recombinant Rhesus Macaque GPC3(Gln25-His559) Protein, C-6*His-tagged HEK293 His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

GPC3 involved in several pathways and played different roles in them. We selected most pathways GPC3 participated on our site, such as Proteoglycans in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Proteoglycans in cancerITGB5;TLR2;FZD7;PIK3CB;VTN;ESR1;PIK3R1;PLAU;SOS1

GPC3 has several biochemical functions, for example, heparan sulfate proteoglycan binding, peptidyl-dipeptidase inhibitor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GPC3 itself. We selected most functions GPC3 had, and list some proteins which have the same functions with GPC3. You can find most of the proteins on our site.

Function Related Protein
heparan sulfate proteoglycan bindingGPC6;CFH;HPSE2;GPC1B;GPC5A;GPC3;Itgam&Itgb2;FST;UBE4A
peptidyl-dipeptidase inhibitor activity
protein bindingZNF232;INTS10;PARN;RPS14;FMNL3;SYT2;PEX11B;CARS;DHDDS

GPC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPC3.

APPL1

Research Area

Related articles

Zaghloul, RA; El-Shishtawy, MM; et al. Evaluation of antiglypican-3 therapy as a promising target for amelioration of hepatic tissue damage in hepatocellular carcinoma. EUROPEAN JOURNAL OF PHARMACOLOGY 746:353-362(2015).
Tretiakova, M; Zynger, DL; et al. Glypican 3 overexpression in primary and metastatic Wilms tumors. VIRCHOWS ARCHIV 466:67-76(2015).
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Customer Reviews (3)

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Reviews
08/12/2020

    The GPC3 protein offered by the manufacturer is of exceptional quality, making it an ideal choice to fulfill my experimental needs.

    09/18/2019

      The technical support provided by the manufacturer is invaluable in overcoming experimental hurdles and optimizing the utilization of GPC3 protein.

      04/10/2019

        Another crucial aspect where the manufacturer excels is their efficient supply chain management.

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