Recombinant Human HMGN1 Protein, GST-tagged

• Cat.No.: HMGN1-4879H
• Product Overview: Human HMGN1 full-length ORF ( AAH23984, 1 a.a. - 100 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Chromosomal protein HMG14 and its close analog HMG17 (MIM 163910) bind to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. The 2 proteins may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Their ubiquitous distribution and relative abundance, as well as the high evolutionary conservation of the DNA-binding domain of the HMG14 family of proteins, suggest that they may be involved in an important cellular function.[supplied by OMIM
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 36.74 kDa
• AA Sequence: MPKRKVSSTEGAAKEEPKRRSARLS AKPPAKVEAKPKKAAAKDKSSDKKV QTKGKRGAKGKQAEVANQETKEDLP AENGETKTEESPASDEAGEKEAKSD
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: HMGN1 high mobility group nucleosome binding domain 1 [ Homo sapiens ]
• Official Symbol: HMGN1
• Synonyms: HMGN1; high mobility group nucleosome binding domain 1; high mobility group (nonhistone chromosomal) protein 14 , high mobility group nucleosome binding domain 1 , HMG14; non-histone chromosomal protein HMG-14; FLJ27265; FLJ31471; high mobility group nucleosome binding 1; MGC104230; MGC117425; nonhistone chromosomal protein HMG 14; nonhistone chromosomal protein HMG-14; high-mobility group nucleosome binding 1; high-mobility group nucleosome binding domain 1; high-mobility group (nonhistone chromosomal) protein 14; high mobility group nucleosome-binding domain-containing protein 1; HMG14
• Gene ID: 3150
• mRNA Refseq: NM_004965
• Protein Refseq: NP_004956
• MIM: 163920
• UniProt ID: P05114