Recombinant Human HSD3B1 Protein, GST-tagged

• Cat.No.: HSD3B1-5078H
• Product Overview: Human HSD3B1 full-length ORF ( AAH31999.1, 1 a.a. - 373 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is an enzyme that catalyzes the oxidative conversion of delta-5-3-beta-hydroxysteroid precursors into delta-4-ketosteroids, which leads to the production of all classes of steroid hormones. The encoded protein also catalyzes the interconversion of 3-beta-hydroxy- and 3-keto-5-alpha-androstane steroids. [provided by RefSeq, Jun 2016]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 66.77 kDa
• AA Sequence: MTGWSCLVTGAGGFLGQRIIRLLVK EKELKEIRVLDKAFGPELREEFSKL QNKTKLTVLEGDILDEPFLKRACQD VSVIIHTACIIDVFGVTHRESIMNV NVKGTQLLLEACVQASVPVFIYTSS IEVAGPNSYKEIIQNGHEEEPLENT WPAPYPHSKKLAEKAVLAANGWNLK NGGTLYTCALRPMYIYGEGSRFLSA SINEALNNNGILSSVGKFSTVNPVY VGNVAWAHILALRALQDPKKAPSIR GQFYYISDDTPHQSYDNLNYTLSKE FGLRLDSRWSFPLSLMYWIGFLLEI VSFLLRPIYTYRPPFNRHIVTLSNS VFTFSYKKAQRDLAYKPLYSWEEAK QKTVEWVGSLVDRHKENLKSKTQ
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 [ Homo sapiens ]
• Official Symbol: HSD3B1
• Synonyms: HSD3B1; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; HSD3B, HSDB3; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1; SDR11E1; short chain dehydrogenase/reductase family 11E; member 1; 3 beta-hydroxysteroid dehydrogenase/Delta 5--> 4-isomerase type 1; 3-beta-HSD I; progesterone reductase; steroid Delta-isomerase; trophoblast antigen FDO161G; delta-5-3-ketosteroid isomerase; 3-beta-hydroxy-5-ene steroid dehydrogenase; 3-beta-hydroxy-Delta(5)-steroid dehydrogenase; short chain dehydrogenase/reductase family 11E, member 1; 4-isomerase type I; hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 1; I; HSD3B; HSDB3; HSDB3A; 3BETAHSD
• Gene ID: 3283
• mRNA Refseq: NM_000862
• Protein Refseq: NP_000853
• MIM: 109715
• UniProt ID: P14060