Recombinant Human IL17RA protein, Fc-Avi-tagged
Cat.No. : | IL17RA-299H |
Product Overview : | Recombinant Human IL-17 RA / CD217 Protein is expressed from Expi293 with a Fc and Avi Tag at the Cterminal. It contains Leu33 - Trp320. |
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Description : | Interleukin 17 (also known as CTLA‑8) is a T cell‑expressed pleotropic cytokine. IL‑17 binds to IL‑17 receptor (IL‑17 R) which shares no homology with any known family of receptors. While the expression of IL‑17 is restricted to activated T cells, the IL‑17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The human IL‑17 R gene was localized to chromosome 22. |
Source : | HEK293 |
Species : | Human |
Tag : | Fc-Avi |
Form : | Supplied as 0.22um filtered solution in 20mM PBS,pH7.4 . |
Molecular Mass : | The protein has a predicted MW of 61.8 kDa.Due to glycosylation, the protein migrates to 78-100 KDa based on Bis-Tris PAGE result |
Protein length : | It contains Leu33 - Trp320 . |
Endotoxin : | Less than 0.05 EU per ug by the LAL method. |
Purity : | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
Storage : | The product should be stored at -70°C. Please do not repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | IL17RA interleukin 17 receptor A [ Homo sapiens ] |
Official Symbol : | IL17RA |
Synonyms : | CD217,CDw217,IL-17RA,IL17R,CANDF5,hIL-17R, IL17RA |
Gene ID : | 23765 |
mRNA Refseq : | NM_014339 |
Protein Refseq : | NP_055154 |
MIM : | 605461 |
UniProt ID : | Q96F46 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionSurface plasmon resonance, co-immunoprecipitation, and mutagenesis studies reveal IL17RA's binding partners and affinity.
Cross-pathway signaling assays, gene expression profiling, and functional rescue experiments unveil IL17RA's interaction networks.
Angiogenesis assays, fibroblast activation assays, and tissue remodeling models illuminate IL17RA's role in tissue repair.
Animal models, pharmacological interventions, and toxicity assessments evaluate IL17RA-targeted therapies and translational challenges.
Patient cohorts, clinical data analysis, and immune profiling provide insights into IL17RA's relevance in autoimmune diseases.
Flow cytometry, in vivo imaging, and chemotaxis assays characterize immune cell responses guided by IL17RA activation.
Phosphorylation assays, gene expression analysis, and knockout models dissect IL17RA-mediated signaling cascades.
Disease models, antibody-based treatments, and inflammatory biomarker assessments elucidate IL17RA's therapeutic potential.
ChIP-sequencing, promoter analysis, and epigenetic modification studies uncover IL17RA gene regulation mechanisms.
Epithelial barrier assays, microbiome analysis, and infection models decipher IL17RA's role in mucosal defense.
Customer Reviews (3)
Write a reviewEffective in T-cell activation.
Suitable for co-immunoprecipitation.
High solubility.
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