Recombinant Human IL2RA Protein, C-Avi&His tagged, Biotinylated
Cat.No. : | IL2RA-43H |
Product Overview : | Biotinylated recombinant Human Interleukin-2 Receptor subunit alpha is produced by our Mammalian expression system and the target gene encoding Glu22-Gln240 is expressed with a Avi and 6His tag at the C-terminus. |
- Specification
- Gene Information
- Related Products
Description : | Interleukin-2 receptor subunit alpha (IL2RA) is a single-pass type I membrane glycoprotein, contains 2 Sushi (CCP/SCR) domains. IL2RA is expressed on activated T cells and regulatory T cells, and can bind IL2 with low affinity by itself. The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. While homodimeric alpha chains (IL2RA) result in low-affinity receptor, homodimeric beta (IL2RB) chains produce a medium-affinity receptor. CD25 has been previously regarded as an activation marker on dendritic cells. Although both murine and human dendritic cells can express CD25, they do not express the beta-chain of the IL-2 receptor, which is indispensable for the execution of IL-2 signaling. |
Source : | HEK293 |
Species : | Human |
Tag : | C-Avi&His |
Protein Length : | Glu22-Gln240 |
Storage Buffer : | Supplied as a 0.2 μm filtered solution of PBS, pH7.4 |
Shipping : | Dry ice/ice pack |
Gene Name : | IL2RA interleukin 2 receptor, alpha [ Homo sapiens (human) ] |
Official Symbol : | IL2RA |
Synonyms : | Interleukin-2 receptor subunit alpha; CD25; p55; TAC antigen; IL2-RA; IL-2R subunit alpha; IL-2-RA; IL2RA; IL-2 receptor subunit alpha |
Gene ID : | 3559 |
mRNA Refseq : | NM_000417 |
Protein Refseq : | NP_000408 |
MIM : | 147730 |
UniProt ID : | P01589 |
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◆ Lysates | ||
IL2RA-2024MCL | Recombinant Mouse IL2RA cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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